Evidence map›Paper›PMID 22423651›Full record

ArticleVeterinary research2012

Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection.

Uladzimir U Karniychuk, Wander Van Breedam, Nadine Van Roy, Claire Rogel-Gaillard, Hans J Nauwynck

Abstract read
In one paragraph

Article in Veterinary research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Samples sizes required to accurately quantify viral load and histologic lesion severity at the maternal-fetal interface of PRRSV-inoculated pregnant gilts.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
    Article
  7. Article
  8. The African strain of Zika virus causes more severeEmerging microbes & infections · 2019
    Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Uladzimir U KarniychukLaboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium. uladzimir.karniychuk@UGent.be.
Wander Van Breedam
Nadine Van Roy
Claire Rogel-Gaillard
Hans J Nauwynck

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of foreign cells within the tissue/circulation of an individual is described as microchimerism. The main purpose of the present investigation was to study if microchimerism occurs in healthy sows/fetuses and if porcine reproductive and respiratory syndrome virus (PRRSV) infection influences this phenomenon. Six dams were inoculated intranasally with PRRSV and three non-inoculated dams served as controls. Male DNA was detected in female fetal sera of all dams via PCR. Male DNA was also detected in the maternal circulation. Sex-typing FISH showed the presence of male cells in the female fetal organs and vice versa. PRRSV infection did not influence microchimerism, but might misuse maternal and sibling microchimeric cells to enter fetuses.

Indexed as

AnimalsChimerismDNAFemaleIn Situ Hybridization, FluorescenceMalePolymerase Chain ReactionPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusPregnancySwineDNA

Identifiers

PMID22423651
PMCPMC3368719

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.