ArticleBeilstein journal of organic chemistry2012
Continuous-flow catalytic asymmetric hydrogenations: Reaction optimization using FTIR inline analysis.
Article in Beilstein journal of organic chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Review
- Light-driven redox deracemization of indolines and tetrahydroquinolines using a photocatalyst coupled with chiral phosphoric acid.Chemical science · 2023Article
- Recent Advances in Homogeneous Catalysts for the Asymmetric Hydrogenation of Heteroarenes.ACS catalysis · 2020Article
- One Amine-3 Tasks: Reductive Coupling of Imines with Olefins in Batch and Flow.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Organic Synthesis Using Environmentally Benign Acid Catalysis.Current organic synthesis · 2019Article
- Generation and Trapping of Ketenes in Flow.European journal of organic chemistry · 2015Article
- 3D-printed devices for continuous-flow organic chemistry.Beilstein journal of organic chemistry · 2013Article
- A combined continuous microflow photochemistry and asymmetric organocatalysis approach for the enantioselective synthesis of tetrahydroquinolines.Beilstein journal of organic chemistry · 2013Article
- Continuous flow photocyclization of stilbenes - scalable synthesis of functionalized phenanthrenes and helicenes.Beilstein journal of organic chemistry · 2013Article
- Raman spectroscopy as a tool for monitoring mesoscale continuous-flow organic synthesis: Equipment interface and assessment in four medicinally-relevant reactions.Beilstein journal of organic chemistry · 2013Article
- Efficient continuous-flow synthesis of novel 1,2,3-triazole-substituted β-aminocyclohexanecarboxylic acid derivatives with gram-scale production.Beilstein journal of organic chemistry · 2013Article
- Continuous parallel ESI-MS analysis of reactions carried out in a bespoke 3D printed device.Beilstein journal of nanotechnology · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The asymmetric organocatalytic hydrogenation of benzoxazines, quinolines, quinoxalines and 3H-indoles in continuous-flow microreactors has been developed. Reaction monitoring was achieved by using an inline ReactIR flow cell, which allows fast and convenient optimization of reaction parameters. The reductions proceeded well, and the desired products were isolated in high yields and with excellent enantioselectivities.
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