ArticleBeilstein journal of organic chemistry2012
The volatiles of pathogenic and nonpathogenic mycobacteria and related bacteria.
Article in Beilstein journal of organic chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 48 citations in OpenAlex.
- Volatile Emissions From Diverse Estuarine Bacteria Share Core Compounds With a Subset of Strain-Specific, Low Abundance Compounds.Environmental microbiology reports · 2026Article
- Volatile organic compound detection of Buruli ulcer disease: Headspace analysis of Mycobacterium ulcerans and used gauzes of Buruli-compatible ulcers.PLoS neglected tropical diseases · 2024Article
- Modern approaches for detection of volatile organic compounds in metabolic studies focusing on pathogenic bacteria: Current state of the art.Journal of pharmaceutical analysis · 2024Review
- Volatile organic compounds emitted byFrontiers in microbiology · 2022Article
- Profiles of Volatile Biomarkers Detect Tuberculosis from Skin.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Identification of volatiles from six marineBeilstein journal of organic chemistry · 2021Article
- Application of Volatilome Analysis to the Diagnosis of Mycobacteria Infection in Livestock.Frontiers in veterinary science · 2021Review
- Screening of Microbial Volatile Organic Compounds for Detection of Disease in Cattle: Development of Lab-scale Method.Scientific reports · 2019Article
- Article
- Comprehensive volatile metabolic fingerprinting of bacterial and fungal pathogen groups.Journal of breath research · 2018Article
- Rapid Screening of Volatile Organic Compounds fromInternational journal of analytical chemistry · 2018Article
- Comparative analysis of volatile organic compounds for the classification and identification of mycobacterial species.PloS one · 2018Article
- Mycobacteria-derived biomarkers for tuberculosis diagnosis.The Indian journal of medical research · 2017Review
- Diagnosis of pulmonary tuberculosis and assessment of treatment response through analyses of volatile compound patterns in exhaled breath samples.The Journal of infection · 2017Article
- Article
- Evaluation of Giant African Pouched Rats for Detection of Pulmonary Tuberculosis in Patients from a High-Endemic Setting.PloS one · 2015Article
- A volatile relationship: profiling an inter-kingdom dialogue between two plant pathogens, Ralstonia Solanacearum and Aspergillus Flavus.Journal of chemical ecology · 2014Article
- Article
- Production of bioactive volatiles by different Burkholderia ambifaria strains.Journal of chemical ecology · 2013Article
- Bacterial volatiles and diagnosis of respiratory infections.Advances in applied microbiology · 2013Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Volatiles released by pathogenic and nonpathogenic mycobacteria, as well as by mycobacteria-related Nocardia spp., were analyzed. Bacteria were cultivated on solid and in liquid media, and headspace samples were collected at various times during the bacterial lifecycle to elucidate the conditions giving optimal volatile emission. Emitted volatiles were collected by using closed-loop stripping analysis (CLSA) and were analyzed by gas-chromatography-mass-spectrometry. A wide range of compounds was produced, although the absolute amount was small. Nevertheless, characteristic bouquets of compounds could be identified. Predominantly aromatic compounds and fatty-acid derivatives were released by pathogenic/nonpathogenic mycobacteria, while the two Nocardia spp. (N. asteroides and N. africana) emitted the sesquiterpene aciphyllene. Pathogenic Mycobacterium tuberculosis strains grown on agar plates produced a distinct bouquet with different volatiles, while liquid cultures produce less compounds but sometimes an earlier onset of volatile production because of their steeper growth curves under this conditions. This behavior differentiates M. tuberculosis from other mycobacteria, which generally produced fewer compounds in seemingly lower amounts. Knowledge of the production of volatiles by M. tuberculosis can facilitate the rational design of alternative and faster diagnostic measures for tuberculosis.
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