ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
Dorsoventral differences in intrinsic properties in developing CA1 pyramidal cells.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 43 citations in OpenAlex.
- Intrinsic Excitability of Rat Hippocampal Granule Cells Increases Along the Dorsal-to-Ventral Axis.Hippocampus · 2026Article
- Kcnq (Kv7) channels exhibit frequency-dependent responses via partial inductor-like gating dynamics.Communications biology · 2025Article
- Distinct GABAergic modulation of timing-dependent LTP in CA1 pyramidal neurons along the longitudinal axis of the mouse hippocampus.iScience · 2024Article
- Validation of the binding stoichiometry between HCN channels and their neuronal regulator TRIP8b by single molecule measurements.Frontiers in physiology · 2022Article
- Ion-channel degeneracy: Multiple ion channels heterogeneously regulate intrinsic physiology of rat hippocampal granule cells.Physiological reports · 2021Article
- Spatio-temporal heterogeneity in hippocampal metabolism in control and epilepsy conditions.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Kv11 (ether-à-go-go-related gene) voltage-dependent KThe Journal of physiology · 2021Article
- The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels.Channels (Austin, Tex.) · 2020Review
- Topographic heterogeneity of intrinsic excitability in mouse hippocampal CA3 pyramidal neurons.Journal of neurophysiology · 2020Article
- Rational design of a mutation to investigate the role of the brain protein TRIP8b in limiting the cAMP response of HCN channels in neurons.The Journal of general physiology · 2020Article
- Heterogeneities in intrinsic excitability and frequency-dependent response properties of granule cells across the blades of the rat dentate gyrus.Journal of neurophysiology · 2020Article
- Reduced intrinsic excitability of CA1 pyramidal neurons in human immunodeficiency virus (HIV) transgenic rats.Brain research · 2019Article
- Short-term dynamics of input and output of CA1 network greatly differ between the dorsal and ventral rat hippocampus.BMC neuroscience · 2019Article
- Stores, Channels, Glue, and Trees: Active Glial and Active Dendritic Physiology.Molecular neurobiology · 2019Review
- [Changes of membrane properties and synaptic stability of rat retinal ganglion cells during postnatal development].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018Article
- Molecular fingerprinting of principal neurons in the rodent hippocampus: A neuroinformatics approach.Journal of pharmaceutical and biomedical analysis · 2017Article
- Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network.Nature communications · 2017Article
- Electrophysiological Properties of CA1 Pyramidal Neurons along the Longitudinal Axis of the Mouse Hippocampus.Scientific reports · 2016Article
- Mapping the electrophysiological and morphological properties of CA1 pyramidal neurons along the longitudinal hippocampal axis.Hippocampus · 2016Article
- A1 adenosine receptor-mediated GIRK channels contribute to the resting conductance of CA1 neurons in the dorsal hippocampus.Journal of neurophysiology · 2015Article
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Authors and funding
11 authors at 7 institutions in 5 countries.
Funding
Abstract
The dorsoventral and developmental gradients of entorhinal layer II cell grid properties correlate with their resonance properties and with their hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channel current characteristics. We investigated whether such correlation existed in rat hippocampal CA1 pyramidal cells, where place fields also show spatial and temporal gradients. Resonance was absent during the first postnatal week, and emerged during the second week. Resonance was stronger in dorsal than ventral cells, in accord with HCN current properties. Resonance responded to cAMP in ventral but not in dorsal cells. The dorsoventral distribution of HCN1 and HCN2 subunits and of the auxiliary protein tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) could account for these differences between dorsal and ventral cells. The analogous distribution of the intrinsic properties of entorhinal stellate and hippocampal cells suggests the existence of general rules of organization among structures that process complementary features of the environment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.