ArticleCanadian family physician Medecin de famille canadien2012
Effectiveness of rotavirus vaccine in preventing severe acute gastroenteritis in children.
Article in Canadian family physician Medecin de famille canadien, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Enteric pathogens associated with gastroenteritis among children under 5 years in sub-Saharan Africa: a systematic review and meta-analysis.Epidemiology and infection · 2020Pooled it
- Article
- Aetiology of childhood viral gastroenteritis in Lucknow, North India.The Indian journal of medical research · 2015Article
- Association between mixed rotavirus vaccination types of infants and rotavirus acute gastroenteritis.Vaccine · 2015Article
- A supplementary home dose of oral ondansetron given in anticipation of recurrent emesis in paediatric acute gastroenteritis.Paediatrics & child health · 2014Article
- Recreational water-related illness: office management and prevention.Canadian family physician Medecin de famille canadien · 2013Review
- Canadian rotavirus vaccine effectiveness data.Canadian family physician Medecin de famille canadien · 2012Article
Corrections and comments
- Commented on by
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
questionAs rotavirus vaccines enter the scheduled immunization programs in Canada, more and more of the children younger than 1 year of age in my practice are receiving rotavirus vaccines. Is there evidence that rotavirus vaccines are effective in preventing acute gastroenteritis complications such as dehydration and hospitalization? ANSWER: To reduce the burden of illness of rotavirus-induced gastroenteritis, 2 orally administered rotavirus vaccines were licensed in recent years. Large studies documented the safety profiles of these vaccines and several provinces introduced a vaccine as part of their immunization program. Recent data from developed and developing countries suggest that the rotavirus vaccine is substantially reducing morbidity and mortality among children. Initial clinical trials are now being supported by effectiveness data from field studies, showing a 70% to 100% reduction in emergency department visits and hospitalizations of children with rotavirus acute gastroenteritis.
Indexed as
Identifiers
22423021PMC3303647W2147684360What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.