ArticleScience (New York, N.Y.)2012
Comment on "Widespread RNA and DNA sequence differences in the human transcriptome".
Article in Science (New York, N.Y.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
118 citing papers in PubMed.
- Article
- Short-read RNA-seq yields lower estimates of A-to-I RNA editing levels than long-read cDNA sequencing.Advanced biotechnology · 2026Article
- A Global Assessment of the Transcription-Dependent Single Nucleotide Variants Relies on the Characteristics of RNA-Sequencing Technologies.Biomolecules · 2026Article
- Systematically developing a registry of splice-site creating variants utilizing massive publicly available transcriptome sequence data.Nature communications · 2025Article
- DEMINING: A deep learning model embedded framework to distinguish RNA editing from DNA mutations in RNA sequencing data.Genome biology · 2024Article
- Robustness and reliability of single-cell regulatory multi-omics with deep mitochondrial mutation profiling.bioRxiv : the preprint server for biology · 2024Article
- ADAR-Mediated A>I(G) RNA Editing in the Genotoxic Drug Response of Breast Cancer.International journal of molecular sciences · 2024Review
- Article
- Critical Differential Expression Assessment for Individual Bulk RNA-Seq Projects.bioRxiv : the preprint server for biology · 2024Article
- RNA editing detection in SARS-CoV-2 transcriptome should be different from traditional SNV identification.Journal of applied genetics · 2022Article
- Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2.Journal of applied genetics · 2022Article
- Landscape of adenosine-to-inosine RNA recoding across human tissues.Nature communications · 2022Article
- Adaptive eQTLs reveal the evolutionary impacts of pleiotropy and tissue-specificity while contributing to health and disease.HGG advances · 2022Article
- The landscape of coding RNA editing events in pediatric cancer.BMC cancer · 2021Article
- Recent technical advances in the study of nucleic acid modifications.Molecular cell · 2021Review
- Repurposing RNA sequencing for discovery of RNA modifications in clinical cohorts.Science advances · 2021Article
- The epitranscriptome beyond mNature reviews. Genetics · 2021Review
- Editing and Chemical Modifications on Non-Coding RNAs in Cancer: A New Tale with Clinical Significance.International journal of molecular sciences · 2021Review
- Neoantigen prediction in human breast cancer using RNA sequencing data.Cancer science · 2021Article
- It's the Little Things (in Viral RNA).mBio · 2020Review
58 more citing papers are in PubMed but not listed here.
Corrections and comments
- Comment on
Authors and funding
3 authors.
Funding
Abstract
Li et al. (Research Articles, 1 July 2011, p. 53; published online 19 May 2011) reported more than 10,000 mismatches between messenger RNA and DNA sequences from the same individuals, which they attributed to previously unrecognized mechanisms of gene regulation. We found that at least 88% of these sequence mismatches can likely be explained by technical artifacts such as errors in mapping sequencing reads to a reference genome, sequencing errors, and genetic variation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.