ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2012
The natural course of nicotine dependence symptoms among adolescent smokers.
Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Electronic Cigarettes Use and Intention to Cigarette Smoking among Never-Smoking Adolescents and Young Adults: A Meta-Analysis.International journal of environmental research and public health · 2016Pooled it
- Factors associated with smoking cessation among adolescents: A retrospective study in a smoking cessation outpatient clinic.Tobacco induced diseases · 2026Article
- Age of onset of nicotine use and severity of nicotine addiction symptoms are associated with hippocampal volume in late adolescents and emerging adults.Frontiers in adolescent medicine · 2025Article
- Article
- Measures of youth e-cigarette use: strengths, weaknesses and recommendations.Frontiers in public health · 2024Article
- Nicotine Dependence among College Students Uninterested in Smoking Cessation during the COVID-19 Pandemic: A Cross-Sectional Survey.International journal of environmental research and public health · 2023Article
- Chronic exposure to cigarette smoke extract increases nicotine withdrawal symptoms in adult and adolescent male rats.Advances in drug and alcohol research · 2023Article
- Characteristics of tobacco use among secondary school students: a cross-sectional study in a school in Valencia, Spain.Frontiers in public health · 2023Article
- Unique effects of nicotine across the lifespan.Pharmacology, biochemistry, and behavior · 2022Review
- Association between cumulative cigarette and Waterpipe smoking and symptoms of dependence in Lebanese adults.BMC public health · 2021Article
- Chronic exposure to cigarette smoke extract upregulates nicotinic receptor binding in adult and adolescent rats.Neuropharmacology · 2020Article
- Nicotine Dependence and Loss of Autonomy among Greek Adolescent Smokers: A Countrywide Cross-Sectional Study.International journal of environmental research and public health · 2020Article
- Tobacco Use Trajectories in Young Adults: Analyses of Predictors Across Systems Levels.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020Article
- Ecological momentary assessment of various tobacco product use among young adults.Addictive behaviors · 2019Article
- The presence and stability of nicotine dependence symptoms among adolescents after the implementation of a smoking prevention program.Tobacco induced diseases · 2019Article
- Cigarette use trajectories in young adults: Analyses of predictors across system levels.Drug and alcohol dependence · 2018Article
- Marijuana use disorder symptoms among recent onset marijuana users.Addictive behaviors · 2017Article
- The Relation between Frequency of E-Cigarette Use and Frequency and Intensity of Cigarette Smoking among South Korean Adolescents.International journal of environmental research and public health · 2017Article
- Can tobacco dependence provide insights into other drug addictions?BMC psychiatry · 2016Review
- Progression of nicotine dependence, mood level, and mood variability in adolescent smokers.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
introductionFew studies have investigated the natural course of nicotine dependence prospectively from the earliest experiences with smoking.
methodsDrawing on a cohort of 9th- and 10th-grade adolescents followed over 48 months, survival analyses were conducted to evaluate the cumulative probability, following smoking initiation, for the development of nicotine dependence symptoms.
resultsAlthough each nicotine dependence symptom was significantly more prevalent among adolescents who had smoked more than 100 cigarettes by the end of the follow-up assessment, 20% of adolescents smoking fewer than 100 cigarettes reported experiencing "smoking to relieve restlessness and irritability" and "smoking a lot more now to be satisfied compared to when first smoked." Nicotine dependence symptoms were also reported before reaching 100 cigarettes for a substantial number of adolescents (between 9.4% and 58.8% for individual symptoms). Endorsement of nicotine dependence symptoms prospectively predicted past-week smoking (odds ratios [ORs] between 3.18 and 14.62 for significant symptoms) and past-month daily smoking (significant symptoms' ORs between 3.52 and 10.68) at the 48-month assessment even when controlling for amount of previous smoking.
conclusionsThe present study adds to the growing body of literature on the natural course of nicotine dependence from earliest experiences with smoking by showing that symptoms of nicotine dependence may develop soon after initiation and/or at low levels of smoking. Our findings suggest that novice adolescent smokers should not be neglected in smoking cessation intervention and that screening and effective intervention for early emerging symptoms among adolescent smokers may be an important target in preventing chronic smoking.
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Registered trials
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