Evidence map›Paper›PMID 22422916›Full record

ArticleBMJ open2012

A question-answer pair (QAP) database integrated with websites to answer complex questions submitted to the Regional Medicines Information and Pharmacovigilance Centres in Norway (RELIS): a descriptive study.

Jan Schjøtt, Linda A Reppe, Pål-Didrik H Roland, Tone Westergren

Abstract read
In one paragraph

Article in BMJ open, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Future Clinical Pharmacological Decision Support.Basic & clinical pharmacology & toxicology · 2026
    Article
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  7. Article
  8. Review
  9. Article
  10. Article
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  12. Benefits of a national network of drug information centres: RELIS.European journal of clinical pharmacology · 2017
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Clinical pharmacology in everyday clinical care.European journal of clinical pharmacology · 2013
    Article
  18. Pharmacovigilance and drug safety 2011 in Calabria (Italy): Adverse events analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jan SchjøttSection of Clinical Pharmacology, Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway.
Linda A Reppe
Pål-Didrik H Roland
Tone Westergren

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess a question-answer pair (QAP) database integrated with websites developed for drug information centres to answer complex questions effectively.

designDescriptive study with comparison of two subsequent 6-year periods (1995-2000 and 2001-2006).

settingThe Regional Medicines Information and Pharmacovigilance Centres in Norway (RELIS).

participantsA randomised sample of QAPs from the RELIS database. PRIMARY OUTCOME MEASURE: Answer time in days compared with Mann-Whitney U test. SECONDARY OUTCOME MEASURE: Number of drugs involved (one, two, three or more), complexity (judgemental and/or patient-related or not) and literature search (none, simple or advanced) compared with χ(2) tests.

results842 QAPs (312 from 1995 to 2000 and 530 from 2001 to 2006) were compared. The fraction of judgemental and patient-related questions increased (66%-75% and 54%-72%, respectively, p<0.01). Number of drugs and literature search (>50% advanced) was similar in the two periods, but the fraction of answers referring to the RELIS database increased (13%-31%, p<0.01). Median answer time was reduced from 2 days to 1 (p<0.01), although the fraction of complex questions increased from the first to the second period. Furthermore, the mean number of questions per employee per year increased from 66 to 89 from the first to the second period.

conclusionsThe authors conclude that RELIS has a potential to efficiently answer complex questions. The model is of relevance for organisation of drug information centres.

Identifiers

PMID22422916
PMCPMC3307033

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.