Evidence map›Paper›PMID 22422631›Full record

GuidelineCA: a cancer journal for clinicians

American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer.

Debbie Saslow, Diane Solomon, Herschel W Lawson, Maureen Killackey, Shalini L Kulasingam, Joanna Cain, Francisco A R Garcia, Ann T Moriarty, Alan G Waxman, David C Wilbur and 10 more

2 registry-linked trialsAbstract readPractice Guideline
In one paragraph

Guideline in CA: a cancer journal for clinicians. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 463 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
463citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04585243 naterminatednot on this map

HPV Self-sampling Among Women at the Penn State Hershey Colposcopy Clinics

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2020 to 2022Enrolled22ConditionsHPVArmsEvalyn Brush
NCT04591977 naterminatednot on this map

HPV Self-sampling Among Women at Penn State Hershey Well Women Appointments

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2021 to 2022Enrolled46ConditionsHPVArmsHPV Self-Sampling Kit (Evalyn Brush)
3 · Its place in the literature

Who cites it

463 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021
    Guideline
  5. Pooled it
  6. Trial
  7. Trial
  8. An RCT to Increase Breast and Colorectal Cancer Screening.American journal of preventive medicine · 2020
    Trial
  9. Article
  10. Review
  11. Article
  12. Female allogeneic hematopoietic cell transplant survivors' perspectives on cervical cancer screening: a retrospective study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  13. Observational
  14. Review
  15. Article
  16. Article
  17. Article
  18. Impact of repeatedly screening negative on cervical cancer risk.Journal of the National Cancer Institute · 2026
    Article
  19. Article
  20. Article

403 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Debbie SaslowCancer Control Science Department, American Cancer Society, Atlanta, GA 30303, USA. debbie.saslow@cancer.org
Diane Solomon
Herschel W Lawson
Maureen Killackey
Shalini L Kulasingam
Joanna Cain
Francisco A R Garcia
Ann T Moriarty
Alan G Waxman
David C Wilbur
Nicolas Wentzensen
Levi S Downs
Mark Spitzer
Anna-Barbara Moscicki
Eduardo L Franco
Mark H Stoler
Mark Schiffman
Philip E Castle
Evan R Myers
ACS-ASCCP-ASCP Cervical Cancer Guideline Committee

Funding

Natural History of HPV Infection to NeoplasiaR37CA051323 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MOSCICKI, ANNA-BARBARA · 2005 to 2014
$15.4M
The EPI-STI Biostatistics and Bioinformatics Core (Cuzick/Wheeler)U19AI113187 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI KONG, ALBERTA SUM-YU · 2014 to 2018
$12.6M
Intramural NIH HHS Z99 CA999999NCI NIH HHS R37 CA051323NCI NIH HHS Y99 CA999999NIAID NIH HHS U19 AI113187
6 · The paper itself

Abstract

An update to the American Cancer Society (ACS) guideline regarding screening for the early detection of cervical precancerous lesions and cancer is presented. The guidelines are based on a systematic evidence review, contributions from 6 working groups, and a recent symposium cosponsored by the ACS, the American Society for Colposcopy and Cervical Pathology, and the American Society for Clinical Pathology, which was attended by 25 organizations. The new screening recommendations address age-appropriate screening strategies, including the use of cytology and high-risk human papillomavirus (HPV) testing, follow-up (eg, the management of screen positives and screening intervals for screen negatives) of women after screening, the age at which to exit screening, future considerations regarding HPV testing alone as a primary screening approach, and screening strategies for women vaccinated against HPV16 and HPV18 infections.

Indexed as

CytodiagnosisEarly Detection of CancerFemaleHumansMass ScreeningPapillomaviridaePapillomavirus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsVaginal Smears

Identifiers

PMID22422631
PMCPMC3801360

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.