Trial reportWorld journal of surgery2012
Assessment of swallowing function impairment in patients with benign goiters and impact of thyroidectomy: a case control study.
Trial report in World journal of surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Thyroidectomy-Related Dysphagia: A Systematic Literature Review.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Swallowing disorders after thyroidectomy: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Pooled it
- Quality of Life in Patients with Benign Non-Toxic Goiter After Surgical Intervention: A Systematic Review and Meta-Analysis.World journal of surgery · 2022Pooled it
- Quality of life (QoL) in patients with benign thyroid goiters (pre- and post-thyroidectomy): a prospective study.World journal of surgery · 2013Trial
- Novel ThyPRO-39-based nomogram for identifying impaired quality of life in Graves' hyperthyroidism outpatients: development and internal validation.Endocrine connections · 2026Article
- Influence of intraoperative electromyographic changes and surgical extent on post-thyroidectomy esophageal motility: a prospective cohort study.Frontiers in endocrinology · 2025Article
- Substernal Goiter: From Definitions to Treatment.Sisli Etfal Hastanesi tip bulteni · 2022Review
- Thyroidectomy-related Swallowing Difficulties: Review of the Literature.Acta clinica Croatica · 2020Review
- Quality of life is not affected by thyroid surgery in nontoxic benign goitre in long-term surveillance-A prospective observational study.Endocrinology, diabetes & metabolism · 2020Article
- The Impact of Esophageal Compression on Goiter Symptoms before and after Thyroid Surgery.European thyroid journal · 2019Article
- Changes in Swallowing Symptoms and Esophageal Motility After Thyroid Surgery: A Prospective Cohort Study.World journal of surgery · 2018Article
- The role of steroid administration in the management of dysphagia in anterior cervical procedures.Neurosurgical review · 2018Review
- The Impact of Goiter and Thyroid Surgery on Goiter Related Esophageal Dysfunction. A Systematic Review.Frontiers in endocrinology · 2018Article
- Postoperative swallowing disorder after thyroid and parathyroid resection.Pragmatic and observational research · 2018Article
- Feasibility of Endoscopic Thyroidectomy via Axilla and Breast Approaches for Larger Goiters: Widening the Horizons.Journal of thyroid research · 2018Article
- The prevalence of post-thyroidectomy chronic asthenia: a prospective cohort study.Langenbeck's archives of surgery · 2017Article
- Post-thyroidectomy chronic asthenia: self-deception or disease?Endocrine · 2015Observational
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSwallowing-related quality of life (QoL) in patients with benign thyroid goiters is not much studied. The aim of this study was to assess swallowing function impairment in patients with benign goiters, compare it to a control population, and also find the impact of thyroidectomy and various factors on the outcome of swallowing function.
methodsWe performed a prospective case-control study from September 2009 to September 2011 which consisted of 124 patients who were to undergo primary thyroid surgery and 100 age- and sex-matched controls. A translated and validated modified swallowing quality-of-life (SWAL-QOL) questionnaire was used to assess patients' perception of dysphagia. Presurgery scores of patients and controls and pre- and postsurgery scores (>6 months after surgery) of patients were compared.
resultsThe mean age of males and females in the control and patient groups were 37.7 vs. 39.5 years and 37.4 vs. 39.8 years, respectively. Twelve patients (9.7%) complained of dysphasia at presentation. Sixty-three patients (50.8%) underwent total thyroidectomy and 61 (49.2%) had hemithyroidectomy at the time of initial evaluation, 75, 23.4, and 1.6% of patients were euthyroid, hyperthyroid, and hypothyroid, respectively. Presurgery scores of patients in all of the 11 domains of the SWAL-QOL were lower compared to those of controls. Comparing separately with the matched controls, females had significant differences in nine domains (except for sleep and fatigue) of the SWAL-QOL questionnaire but males did not. Postoperatively, both male and female patients showed significant improvement in the scores of all the domains. Female gender, hyperthyroidism, thyroid nodularity, retrosternal extension, procedure, and weight of the resected specimen were the factors associated with significant improvement in various domains.
conclusionDysphagia seems to be an underestimated problem in patients with benign goiters. Uncomplicated thyroidectomy results in significant improvement in swallowing-related QoL irrespective of patient profile and extent of thyroidectomy.
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