ArticleLancet (London, England)2012
The interleukin-6 pathway and atherosclerosis.
Article in Lancet (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interleukin-6 receptor pathways in abdominal aortic aneurysm.European heart journal · 2013Pooled it
- Plasma interleukin 6 levels are associated with cardiac function after ST-elevation myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Trial
- Adipocytokines, C-reactive protein, and cardiovascular disease: a population-based prospective study.PloS one · 2015Trial
- From Bench to Clinic: Advances in Anti-Inflammatory Therapies for Atherosclerotic Coronary Artery Disease.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Review
- Predisposition to atherosclerosis in children and adults with trisomy 21: biochemical and metabolomic studies.Pediatric endocrinology, diabetes, and metabolism · 2023Article
- Sex-specific association between inflammation and endothelial function relevant gene and vulnerable carotid plaque.Frontiers in physiology · 2022Article
- COVID-19: The Impact on Cardiovascular System.Biomedicines · 2021Review
- Multifactorial expression of IL-6 with update on COVID-19 and the therapeutic strategies of its blockade (Review).Experimental and therapeutic medicine · 2021Review
- Targeted Therapy in Cardiovascular Disease: A Precision Therapy Era.Frontiers in pharmacology · 2021Review
- Article
- Physical Function and Strength in Relation to Inflammation in Older Adults with Obesity and Increased Cardiometabolic Risk.The journal of nutrition, health & aging · 2019Article
- Interleukin 6 Inhibition and Coronary Artery Disease in a High-Risk Population: A Prospective Community-Based Clinical Study.Journal of the American Heart Association · 2017Article
- Spotlight on sirukumab for the treatment of rheumatoid arthritis: the evidence to date.Drug design, development and therapy · 2016Review
- Interleukin-6 Receptor Inhibition Prevents Descending Thoracic Aortic Aneurysm Formation.The Annals of thoracic surgery · 2015Article
- Review
- Interleukin-6 May Contribute to Mortality in Parkinson's Disease Patients: A 4-Year Prospective Study.Parkinson's disease · 2015Article
- Interleukin-6 receptor rs7529229 T/C polymorphism is associated with left main coronary artery disease phenotype in a Chinese population.International journal of molecular sciences · 2014Article
- Interleukin-10 protects against aging-induced endothelial dysfunction.Physiological reports · 2013Article
- Small-molecule inhibitors of signal transducer and activator of transcription 3 protect against angiotensin II-induced vascular dysfunction and hypertension.Hypertension (Dallas, Tex. : 1979) · 2013Article
- IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.International journal of biological sciences · 2012Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
22421338What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.