Evidence map›Paper›PMID 22421240›Full record

ReviewEpileptic disorders : international epilepsy journal with videotape2012

Starting at the beginning: the neuropsychological status of children with new-onset epilepsies.

Bruce P Hermann, Jana E Jones, Daren C Jackson, Michael Seidenberg

Abstract readReview
In one paragraph

Review in Epileptic disorders : international epilepsy journal with videotape, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
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  16. Cognitive development in children with new onset epilepsy.Developmental medicine and child neurology · 2014
    Article
  17. Cognitive outcome of status epilepticus in children.Epilepsy research and treatment · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bruce P HermannDepartment of Neurology, University of Wisconsin School of Medicine, Public Health, Madison WI 5307056, USA. hermann@neurology.wisc.edu
Jana E Jones
Daren C Jackson
Michael Seidenberg

Funding

Neuropsychological Progression of New Onset EpilepsyR01NS044351 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI HERMANN, BRUCE PHILLIP · 2003 to 2015
$6.3M
NINDS NIH HHS R01 NS044351PHS HHS R01-44351
6 · The paper itself

Abstract

This review examines the neurodevelopmental contribution to the cognitive and behavioural complications of epilepsy. Following a brief review of the lifespan complications of childhood epilepsies, attention turns to cognitive, psychiatric and social correlates of childhood epilepsies reported in population-based and tertiary care studies. The focus then becomes the neurobehavioural status of children with new-onset epilepsy; a point in time not confounded by the effects of years of recurrent seizures, medications, and social reactions to epilepsy. Recent research shows that abnormalities in cognition, brain structure and behaviour are present at or near the time of diagnosis. Further, careful history taking indicates that neurobehavioural problems may be present in advance of the first seizure suggesting the potential influence of epileptogenesis, antecedent neurodevelopmental abnormalities, genetic and environmental susceptibilities, and other risk factors. This becomes the substrate upon which to characterise the effects of epilepsy and its treatment on subsequent neurodevelopment. The review concludes with suggestions for future clinical care and research.

Indexed as

AttentionCognitionChildChild, PreschoolEpilepsyHumansNeuropsychological TestsSocial Behavior

Identifiers

PMID22421240
PMCPMC3701720

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.