Evidence map›Paper›PMID 22420726›Full record

ReviewPediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society2012

Ewing sarcoma/peripheral primitive neuroectodermal tumor and related tumors.

Maria Tsokos, Rita D Alaggio, Louis P Dehner, Paul S Dickman

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 78 citations in OpenAlex.

  1. The Diagnostic Quandary of Primary Renal Ewing's Sarcoma onWorld journal of nuclear medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Paratesticular Ewing's sarcoma.Radiology case reports · 2023
    Article
  9. Article
  10. Surgical treatment of pediatric thoracic Ewing tumors.Turk gogus kalp damar cerrahisi dergisi · 2023
    Article
  11. Article
  12. Other Less Prevalent Tumors of the Central Nervous System.Advances in experimental medicine and biology · 2023
    Article
  13. Peripheral primitive neuroectodermal tumor: a case report.Journal of medical case reports · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Primary gastric Ewing sarcoma/primitive neuroectodermal tumor.The Journal of international medical research · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Maria TsokosDepartment of Pathology, National Institutes of Health, Bethesda, MD, USA.
Rita D Alaggio
Louis P Dehner
Paul S Dickman
Barnes-Jewish Hospital · USNational Institutes of Health · USPhoenix Children's Hospital · USUniversity of Padua · IT

Funding

Regulation of Apoptosis in Ewings Sarcoma and NeuroblastomaZIASC010058 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI TSOKOS, MARIA · 2009 to 2012
$1.6M
Histologic and Molecular Characterization of Solid Pediatric TumorsZICSC009431 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI TSOKOS, MARIA · 2009 to 2012
$1.3M
MOLECULAR CHARACTERIZATION OF SOLID PEDIATRIC TUMORSZ01SC009431 · SC · DIVISION OF CLINICAL SCIENCES - NCI · PI TSOKOS, MARIA · 1996 to 2008
$685k
Intramural NIH HHS Z01 SC009431Intramural NIH HHS ZIA SC010058
6 · The paper itself

Abstract

Ewing sarcoma/peripheral primitive neuroectodermal tumor (EWS/pPNET) and other tumors with EWS gene rearrangements encompass a malignant and intermediate neoplasm with a broad anatomic distribution and a wide age range but a predilection for soft tissue in children, adolescents, and young adults. The overlapping histologic, immunohistochemical and cytogenetic and molecular genetic features create diagnostic challenges despite significant clinical and prognostic differences. Ewing sarcoma is the 3rd most common sarcoma in children and adolescents, and desmoplastic small round cell tumor is a rare neoplasm that occurs more often in older children, adolescents, and young adults. Pathologic examination is complemented by immunohistochemistry, cytogenetics, and molecular genetics. This article reviews the clinicopathologic features of EWS/pPNET and desmoplastic small round cell tumor in the spectrum of tumors with EWS gene rearrangements. Other tumors with different histopathologic features and an EWS gene rearrangement are discussed elsewhere in this volume.

Indexed as

Desmoplastic Small Round Cell TumorNeuroectodermal Tumors, Primitive, PeripheralSarcoma, EwingAdolescentChildGene RearrangementHumansRNA-Binding Protein EWSYoung AdultRNA-Binding Protein EWS

Identifiers

PMID22420726
PMCPMC6993191
OpenAlexW2040881903

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.