Evidence map›Paper›PMID 22419867›Full record

ArticleInternational journal of nanomedicine2012

Biochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus.

P Daisy, K Saipriya

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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  7. Antibiotics (Basel, Switzerland) · 2023
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  18. Phytosynthesis of Titanium Dioxide Nanoparticles Using King of BitterBioinorganic chemistry and applications · 2021
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P DaisyPostgraduate and Research Department of Biotechnology and Bioinformatics, Holy Cross College, Teppakulam, Trichy, Tamil Nadu, India. daisylesslie@gmail.com
K Saipriya

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cassia fistula stem bark was used for the preparation of aqueous extract and synthesis of gold nanoparticles to evaluate the hypoglycemic effects of the plant. The synthesized gold nanoparticles were characterized by ultraviolet-visible spectroscopy for their absorbance pattern, Fourier transform infrared spectroscopy to identify possible functional groups, and scanning electron microscopy to determine the size of the nanoparticles. The present investigation reports the efficacy of the gold nanoparticles as promising in the treatment of hyperglycemia. Body weight, serum glucose concentrations, liver function tests, kidney function tests, and lipid profile were analyzed. A significantly larger decrease in serum biochemistry parameters and an increase in body weight, total protein levels, and high-density lipoprotein were observed in rats with streptozotocin-induced diabetes treated with gold nanoparticles than in the ones treated with the aqueous extract. The results of this study confirm that C. fistula gold nanoparticles have promising antidiabetic properties.

Indexed as

Analysis of VarianceAnimalsBlood GlucoseBody WeightCassiaCreatinineDiabetes Mellitus, ExperimentalDrug CarriersGoldHemoglobinsHypoglycemic AgentsLipidsLiverMaleMetal NanoparticlesPlant BarkBlood GlucoseCreatinineDrug CarriersGoldHemoglobinsHypoglycemic AgentsLipidsPlant ExtractsUreaUric Acidaqueousbiochemical analysisCassia fistuladiabetes mellitusgold nanoparticles

Identifiers

PMID22419867
PMCPMC3299574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.