Evidence map›Paper›PMID 22419334›Full record

SynthesisThe Cochrane database of systematic reviews2012

Mirror therapy for improving motor function after stroke.

Holm Thieme, Jan Mehrholz, Marcus Pohl, Johann Behrens, Christian Dohle

5 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 53 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 5 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02548234 nacompletednot on this mapstarted 2015, after this paper: background citation

Effect of Mirror Therapy Versus Bilateral Arm Training for Rehabilitation After Chronic Stroke: a Pilot Randomized-controlled Trial

TypeinterventionalSponsorChina Medical University HospitalRan2015 to 2017Enrolled29ConditionsStrokeArmsMirror therapy, Bilateral arm training
NCT02778087 naterminatednot on this mapstarted 2017, after this paper: background citation

Self-directed Box (Mirror) Therapy After Stroke: A Dosing Study

TypeinterventionalSponsorColumbia UniversityRan2017 to 2018Enrolled8ConditionsStrokeArmsMirror Box Therapy, Sham Mirror Box Therapy
NCT02942875 nacompletednot on this mapstarted 2014, after this paper: background citation

Motor Recovery of the Severely Impaired Paretic Upper Limb After Mirror Therapy in Sub-acute Stroke

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2014 to 2016Enrolled35ConditionsStrokeArmsmirror therapy, control therapy
NCT03418883 nacompletednot on this mapstarted 2014, after this paper: background citation

Effectiveness of Mirror Therapy in Upper Limb Rehabilitation Early After Stroke

TypeinterventionalSponsorCasa di Cura Privata del Policlinico SpARan2014 to 2016Enrolled40ConditionsStroke, AcuteArmsMirror therapy
NCT03582397 nacompletednot on this mapstarted 2017, after this paper: background citation

Virtual Reality Mirror Therapy for Upper Limb Rehabilitation Following Stroke

TypeinterventionalSponsorColumbia UniversityRan2017 to 2018Enrolled11ConditionsStrokeArmsVirtual Reality Mirror Therapy
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 5 syntheses or guidelines pooled it, 135 citations in OpenAlex.

  1. Pooled it
  2. Mirror therapy for improving motor function after stroke.The Cochrane database of systematic reviews · 2018
    Pooled it
  3. Pooled it
  4. Interventions for improving upper limb function after stroke.The Cochrane database of systematic reviews · 2014
    Pooled it
  5. Mirror therapy for improving motor function after stroke.The Cochrane database of systematic reviews · 2012
    Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Inter-lateral Referral of Sensation in Health and Disease Using a Mirror Illusion-A Scoping Review.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2022
    Article
  18. Article
  19. Contralaterally controlled functional electrical stimulation immediately improves hand function.Japanese journal of comprehensive rehabilitation science · 2022
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Holm ThiemeErste Europäische Schule für Physiotherapie, Ergotherapie und Logopädie, Klinik Bavaria Kreischa, Kreischa, Sachen, Germany. holm.thieme@physiotherapie-schule-kreischa.de.
Jan Mehrholz
Marcus Pohl
Johann Behrens
Christian Dohle
Klinik Bavaria · DECharité - Universitätsmedizin Berlin · DEMartin Luther University Halle-Wittenberg · DE

Funding

Chief Scientist Office CZB/4/784
6 · The paper itself

Abstract

backgroundMirror therapy is used to improve motor function after stroke. During mirror therapy, a mirror is placed in the patient's midsagittal plane, thus reflecting movements of the non-paretic side as if it were the affected side.

objectivesTo summarise the effectiveness of mirror therapy for improving motor function, activities of daily living, pain and visuospatial neglect in patients after stroke. SEARCH

methodsWe searched the Cochrane Stroke Group's Trials Register (June 2011), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 2), MEDLINE (1950 to June 2011), EMBASE (1980 to June 2011), CINAHL (1982 to June 2011), AMED (1985 to June 2011), PsycINFO (1806 to June 2011) and PEDro (June 2011). We also handsearched relevant conference proceedings, trials and research registers, checked reference lists and contacted trialists, researchers and experts in our field of study. SELECTION CRITERIA: We included randomised controlled trials (RCTs) and randomised cross-over trials comparing mirror therapy with any control intervention for patients after stroke. DATA COLLECTION AND ANALYSIS: Two review authors independently selected trials based on the inclusion criteria, documented the methodological quality of studies and extracted data. We analysed the results as standardised mean differences (SMDs) for continuous variables. MAIN

resultsWe included 14 studies with a total of 567 participants that compared mirror therapy with other interventions. When compared with all other interventions, mirror therapy may have a significant effect on motor function (post-intervention data: SMD 0.61; 95% confidence interval (CI) 0.22 to 1.0; P = 0.002; change scores: SMD 1.04; 95% CI 0.57 to 1.51; P < 0.0001). However, effects on motor function are influenced by the type of control intervention. Additionally, mirror therapy may improve activities of daily living (SMD 0.33; 95% CI 0.05 to 0.60; P = 0.02). We found a significant positive effect on pain (SMD -1.10; 95% CI -2.10 to -0.09; P = 0.03) which is influenced by patient population. We found limited evidence for improving visuospatial neglect (SMD 1.22; 95% CI 0.24 to 2.19; P = 0.01). The effects on motor function were stable at follow-up assessment after six months. AUTHORS'

conclusionsThe results indicate evidence for the effectiveness of mirror therapy for improving upper extremity motor function, activities of daily living and pain, at least as an adjunct to normal rehabilitation for patients after stroke. Limitations are due to small sample sizes of most included studies, control interventions that are not used routinely in stroke rehabilitation and some methodological limitations of the studies.

Indexed as

Recovery of FunctionStroke RehabilitationActivities of Daily LivingExercise Movement TechniquesFunctional LateralityHumansParesisRandomized Controlled Trials as TopicStroke

Identifiers

PMID22419334
PMCPMC6464769
OpenAlexW4210357214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.