Evidence map›Paper›PMID 22419176›Full record

ArticleFamilial cancer2012

The evolution of personalized cancer genetic counseling in the era of personalized medicine.

Hetal S Vig, Catharine Wang

Registry-linked trialAbstract readLetter
In one paragraph

Article in Familial cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03006913 (Comparison of 3 Modes of Genetic Counseling in High-Risk Public Hospital), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03006913 nacompletednot on this mapstarted 2017, after this paper: background citation

Comparison of 3 Modes of Genetic Counseling in High-Risk Public Hospital

TypeinterventionalSponsorUniversity of California, San FranciscoRan2017 to 2019Enrolled1,273ConditionsGenetic CounselingArmsIn-person, By phone, By video
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Disparities in uptake of BRCA1/2 genetic testing in a randomized trial of telephone counseling.Genetics in medicine : official journal of the American College of Medical Genetics · 2015
    Trial
  2. Preparing for the unexpected: Recommendations for returning secondary findings in late-stage cancer care.Genetics in medicine : official journal of the American College of Medical Genetics · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Finding all BRCA pathogenic mutation carriers: best practice models.European journal of human genetics : EJHG · 2016
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hetal S Vig
Catharine Wang

Funding

Communication of Genetic and Environmental Risks in Colorectal Cancer PreventionK07CA131103 · NCI · FOX CHASE CANCER CENTER · PI WANG, CATHARINE · 2008 to 2012
$674k
NCI NIH HHS K07 CA131103
6 · The paper itself

Abstract

Practice changes in cancer genetic counseling have occurred to meet the demand for cancer genetic services. As cancer genetics continues to impact not only prevention strategies but also treatment decisions, current cancer genetic counseling models will need to be tailored to accommodate emerging clinical indications. These clinical indications include: surgical prophylactic bilateral mastectomy candidates, PARP-inhibitor candidates, patients with abnormal tumor screening results for Lynch syndrome, and post-test counseling patients (after genetic testing is ordered by another healthcare provider). A more personalized, multidisciplinary approach to selecting the best framework, for a given clinical indication, may become increasingly necessary in this era of personalized medicine.

Indexed as

Precision MedicineBreast NeoplasmsColorectal Neoplasms, Hereditary NonpolyposisFemaleGenetic CounselingHeterozygoteHumansMicrosatellite Instability

Identifiers

PMID22419176
PMCPMC3905734

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.