Evidence map›Paper›PMID 22418592›Full record

ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2012

Limb segment load inhibits post activation depression of soleus H-reflex in humans.

Shih-Chiao Tseng, Richard K Shields

Abstract read
In one paragraph

Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Limb compressive load does not inhibit post activation depression of soleus H-reflex in indiviudals with chronic spinal cord injury.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2013
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shih-Chiao TsengPhysical Therapy & Rehabilitation Science Department, University of Iowa, Carver College of Medicine, Iowa City, IA 52242, USA.
Richard K Shields

Funding

Mechanical stress and skeletal plasticity after spinal cord injury in humansR01HD062507 · NICHD · UNIVERSITY OF IOWA · PI SHIELDS, RICHARD K. · 2010 to 2014
$1.5M
NICHD NIH HHS R01 HD062507NICHD NIH HHS R01HD062507
6 · The paper itself

Abstract

objectiveWe investigated the effect of various doses of limb segment load on soleus H-reflex amplitude and post activation depression in healthy individuals. We also explored the influence of limb segment load on spinal circuitry in one individual with chronic SCI.

methodsTwenty-eight healthy adults and one SCI subject received compressive loads applied to the top of their knee at varied doses of load (10%, 25%, and 50% of the body weight). Soleus H-reflexes were measured before (baseline) and during the loading phase.

resultsThere were no significant differences in H-reflex amplitudes during the 50% BW load-on phase as compared to either baseline session or the load-off phase. However, the post activation depression was decreased over 9% (p<0.05) during the load-on phase compared to the load-off phase and scaled according to load (50%>25%>10%). The post activation depression ratio also appears less responsive to varying loads after chronic SCI.

conclusionsLimb segment load decreases post-activation depression in humans. These findings suggest that the mechanism associated with post activation depression is modulated by limb segment load, and may be influenced by spinal reorganization after SCI. SIGNIFICANCE: Future studies will determine if various levels of spasticity modulate the response of limb segment load on post activation depression in those with acute and chronic SCI.

Indexed as

Weight-BearingAdultElectric StimulationElectromyographyExtremitiesFemaleH-ReflexHumansLong-Term Synaptic DepressionMaleMiddle AgedMuscle, SkeletalSpinal Cord InjuriesTime FactorsYoung Adult

Identifiers

PMID22418592
PMCPMC3380139

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.