Evidence map›Paper›PMID 22417783›Full record

ReviewThe Journal of nutritional biochemistry2012

Circadian clock genes and implications for intestinal nutrient uptake.

Anita Balakrishnan, Ali Tavakkolizadeh, David B Rhoads

Abstract readReview
In one paragraph

Review in The Journal of nutritional biochemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Chrononutrition: Potential, Challenges, and Application in Managing Obesity.International journal of molecular sciences · 2025
    Review
  2. Animals : an open access journal from MDPI · 2021
    Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Anita BalakrishnanDepartment of Surgery, Brigham and Women's Hospital, and Department of Surgery, Harvard Medical School, Boston, Massachusetts 02115, USA. anita.balakrishnan@doctors.org.uk
Ali Tavakkolizadeh
David B Rhoads
Harvard University · USBrigham and Women's Hospital · US

Funding

SURGERY AND INTESTINAL ADAPTATIONR01DK047326 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI ASHLEY, STANLEY W · 1999 to 2005
$983k
NIDDK NIH HHS R01 DK047326
6 · The paper itself

Abstract

There has recently been increasing interest in the phenomenon of circadian rhythmicity. We have used circadian rhythms as a means to understanding the regulation of glucose absorption in the intestine. We and others have previously demonstrated rhythmicity in intestinal glucose uptake, mediated by rhythmicity in the expression of the sodium glucose cotransporter 1. Rhythmicity of clock gene expression was subsequently confirmed in the intestine, a phenomenon also demonstrated in other viscera. Clock genes have since been shown via a combination of in vitro and in vivo techniques to play a role in the transcriptional regulation of key absorptive proteins.

Indexed as

Nutritional Physiological PhenomenaAnimalsBiological TransportCircadian ClocksGene Expression RegulationGlucoseHumansIntestinal MucosaSodium-Glucose Transporter 1GlucoseSodium-Glucose Transporter 1

Identifiers

PMID22417783
PMCPMC3331921
OpenAlexW2104590568

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.