Evidence map›Paper›PMID 22415867›Full record

ArticleJournal of general internal medicine2012

Racial and ethnic differences in cardio-metabolic risk in individuals with undiagnosed diabetes: National Health and Nutrition Examination Survey 1999-2008.

Kelly J Hunt, Mulugeta Gebregziabher, Leonard E Egede

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Prevalence and predictors of delayed clinical diagnosis of Type 2 diabetes: a longitudinal cohort study.Diabetic medicine : a journal of the British Diabetic Association · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Kelly J HuntRalph H. Johnson Department of Veterans Affairs Medical Center, Charleston, SC, USA. huntke@musc.edu
Mulugeta Gebregziabher
Leonard E Egede
Medical University of South Carolina · USRalph H. Johnson VA Medical Center · USUnited States Department of Veterans Affairs · US

Funding

Technology Intensified Diabetes Education Study in AA with T2DM (TIDES)K24DK093699 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI EGEDE, LEONARD E. · 2011 to 2020
$1.5M
Trans-generational Impact of Maternal Obesity and Diabetes on Health DisparitiesR01MD004251 · NIMHD · CLEMSON UNIVERSITY · PI HUNT, KELLY J, MAYORGA, MARIA ESTHER · 2009 to 2011
$733k
NIDDK NIH HHS K24 DK093699NIMHD NIH HHS R01 MD004251NIMHD NIH HHS R01-MD004251
6 · The paper itself

Abstract

backgroundAlthough early recognition and treatment of diabetes may be essential to prevent complications, roughly one-fifth of diabetes remains undiagnosed.

objectiveExamine cardio-metabolic risk factors and their control in non-Hispanic white (NHW), non-Hispanic black (NHB) and Mexican American (MA) individuals with undiagnosed diabetes.

designNationally representative cross-sectional study of participants in the National Health and Nutrition Examination Survey (NHANES) continuous cycles conducted 1999 through 2008.

participantsOf 22,621 non-pregnant individuals aged ≥20 years, 2521 had diagnosed diabetes. Of the remaining 20,100 individuals, 17,963 had HbA1c measured, 551 of whom were classified as having undiagnosed diabetes and comprise the study population. MAIN MEASURES: Undiagnosed diabetes was defined as HbA1c ≥ 6.5% without a self-report of physician diagnosed diabetes. Cardio-metabolic risk factor control was examined using regression methods for complex survey data. KEY

resultsAmong individuals with undiagnosed diabetes, mean HbA1c level was 7.7% (95% CI: 7.5, 7.9), 19.3% (95% CI: 14.2, 24.3) smoked, 59.7% (95% CI: 54.5, 64.8%) had hypertension and 96.5% (95% CI: 94.6, 98.4%) had dyslipidemia. Lipid profiles were remarkably different across racial-ethnic groups: NHB had the highest LDL- and HDL-cholesterol, but the lowest triglycerides, while MA had the highest triglycerides and the lowest LDL-cholesterol. After adjusting for age, sex, NHANES examination cycle and use of either blood pressure or lipid medication, the odds of having blood pressure ≥130/80 mmHg was higher in NHB [1.92 (95% CI: 1.09, 3.55)] than NHW, while the odds of having LDL-cholesterol >100 mg/dl was higher in NHW[2.93 (95% CI: 1.37, 6.24)] and NHB[3.34 (95% CI: 1.08, 10.3)] than MA.

conclusionsIn a nationally representative sample of individuals with undiagnosed diabetes, cardio-metabolic risk factor levels were high across all racial/ethnic groups, but NHB and MA had poorer control compared to NHW. Interventions that target identification of diabetes and treatment of cardio-metabolic risk factors are needed.

Indexed as

AdultAgedBlack or African AmericanBlood GlucoseBlood PressureCross-Sectional StudiesDiabetes MellitusEthnicityHumansHyperlipidemiasHypertensionMaleMexican AmericansMiddle AgedNutrition SurveysRacial GroupsBlood Glucose

Identifiers

PMID22415867
PMCPMC3403154
OpenAlexW2000510831

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.