Evidence map›Paper›PMID 22415473›Full record

ReviewCurrent HIV/AIDS reports2012

HIV-1 prevention for HIV-1 serodiscordant couples.

Kathryn Curran, Jared M Baeten, Thomas J Coates, Ann Kurth, Nelly R Mugo, Connie Celum

Open access · greenAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

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  19. Dual contraceptive method use in HIV-serodiscordant Kenyan couples.The journal of family planning and reproductive health care · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Kathryn CurranInternational Clinical Research Center, Department of Global Health, University of Washington, Seattle, WA 98104, USA. kgcurran@uw.edu
Jared M Baeten
Thomas J Coates
Ann Kurth
Nelly R Mugo
Connie Celum
University of Washington · USNational Clinical Research · USNew York University · USUniversity of California System · USUniversity of Nairobi · KE

Funding

Optimizing Antiretroviral-Based HIV Prevention for HIV Serodiscordant CouplesR01MH095507 · NIMH · UNIVERSITY OF WASHINGTON · PI BAETEN, JARED · 2011 to 2020
$6.1M
Multi-component, Targeted HIV Prevention for sub-Saharan Africa: PreventionRxR01AI083034 · NIAID · UNIVERSITY OF WASHINGTON · PI CELUM, CONNIE L · 2009 to 2012
$4.3M
Evaluation of antiretroviral HIV prevention in African HIV discordant couplesR21NR012663 · NINR · UNIVERSITY OF WASHINGTON · PI BAETEN, JARED · 2011 to 2012
$376k
NIAID NIH HHS R01 AI083034NIMH NIH HHS R01 MH095507NINR NIH HHS R21 NR012663
6 · The paper itself

Abstract

A substantial proportion of HIV-1 infected individuals in sub-Saharan Africa are in stable relationships with HIV-1 uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling about risk reduction, and referrals to HIV-1 treatment, reproductive health services, and support services. Maximizing HIV-1 prevention for HIV-1 serodiscordant couples requires a combination of strategies, including counseling about condoms, sexual risk, fertility, contraception, and the clinical and prevention benefits of antiretroviral therapy (ART) for the HIV-1-infected partner; provision of clinical care and ART for the HIV-1-infected partner; antenatal care and services to prevent mother-to-child transmission for HIV-1-infected pregnant women; male circumcision for HIV-1-uninfected men; and, pending guidelines and demonstration projects, oral pre-exposure prophylaxis (PrEP) for HIV-1-uninfected partners.

Indexed as

HIV-1HIV SeronegativityHIV SeropositivityAfricaAnti-Retroviral AgentsFamily Planning ServicesFemaleHeterosexualityHIV InfectionsHumansMalePreventive Health ServicesRisk FactorsSexual BehaviorSexual PartnersAnti-Retroviral Agents

Identifiers

PMID22415473
PMCPMC3570050
OpenAlexW2011362666

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.