Evidence map›Paper›PMID 22415440›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2013

Evaluation of surgical outcomes of retro-rectus versus intraperitoneal reinforcement with bio-prosthetic mesh in the repair of contaminated ventral hernias.

M J Rosen, G Denoto, K M F Itani, C Butler, D Vargo, J Smiell, R Rutan

2 registry-linked trialsAbstract readComparative StudyControlled Clinical TrialMulticenter Study
PubMed Publisher
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00617357 nacompletednot on this map

A Multicenter, Prospective, Observational Evaluation of Repair of Infected or Contaminated Hernias (RICH) Using LTM

TypeinterventionalSponsorLifeCellRan2007 to 2010Enrolled83ConditionsHerniaArmsLTM (Strattice Reconstructive Tissue Matrix)
NCT03702153 nacompletednot on this map

The Use of Synthetic Mesh in Contaminated and Infected Abdominal Wall Repairs: Challenging the Dogma of an Absolute Contra-indication. A Long-term Prospective Clinical Trial

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2012 to 2018Enrolled80ConditionsAbdominal Wall Defect, Abdominal Wall Infection, Abdominal Wall Fistula, InfectionArmsAbdominal wall reconstruction
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Abdominal wall reinforcement: biologic vs. degradable synthetic devices.Hernia : the journal of hernias and abdominal wall surgery · 2017
    Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. [Use of biological meshes in abdominal wall reconstruction. Results of a survey in Germany].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2015
    Article
  18. Onlay ventral hernia repairs using porcine non-cross-linked dermal biologic mesh.Hernia : the journal of hernias and abdominal wall surgery · 2014
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

M J RosenDivision of GI and General Surgery, Case Medical Center, University Hospitals of Cleveland, Cleveland, OH 44106, USA. michael.rosen@uhhospitals.org
G Denoto
K M F Itani
C Butler
D Vargo
J Smiell
R Rutan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHernia repairs in contaminated fields are often reinforced with a bioprosthetic mesh. When choosing which of the multiple musculofascial abdominal wall planes provides the most durable repair, there is little guidance. We hypothesized that the retro-rectus plane would reduce recurrence rates versus intraperitoneal placement due to greater surface area contact of mesh with well-vascularized tissue.

methodsForty-nine of the 80 patients in an ongoing, prospective, multicenter study of contaminated ventral hernia repairs (RICH study, NCT00617357) achieved fascial closure after musculofascial centralization and reinforcement with non-crosslinked porcine acellular dermal matrix (Strattice™, LifeCell, Branchburg, NJ) and were retrospectively analyzed. The Strattice was placed in the retro-rectus position in 23 patients and in the intraperitoneal position in 26.

resultsSubjects were comparable in age, obesity, prior wound infection, presence of a stoma, and infected mesh removal (p > 0.05). More smokers were present in the intraperitoneal group (p = 0.02). Retro-rectus defects were significantly wider and had larger area than the intraperitoneal repairs. At the 1-year follow-up, 44 (90%) of patients were available for review. There was no difference in wound infections, seromas, or hematomas. Recurrent hernias were identified in 10% of retro-rectus repairs and 30% of intraperitoneal repairs (p = 0.14).

conclusionsIn this retrospective analysis of a prospective multicenter study of large, contaminated ventral hernias, despite a larger hernia defect in the retro-rectus group, placement of the mesh in the retro-rectus compartment resulted in a similar recurrence rate to intraperitoneal mesh placement. Ongoing evaluation is important to establish longer-term outcomes and the validity of these findings.

Indexed as

BioprosthesisSurgical MeshAdultAgedCollagenFemaleHematomaHernia, VentralHerniorrhaphyHumansMaleMiddle AgedRecurrenceSeromaSurgical Wound DehiscenceSurgical Wound InfectionCollagenstrattice

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.