ArticleG3 (Bethesda, Md.)2012
Coding Gene Single Nucleotide Polymorphism Mapping and Quantitative Trait Loci Detection for Physiological Reproductive Traits in Brook Charr, Salvelinus fontinalis.
Article in G3 (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Polymorphisms and Expression Characteristics of theAnimals : an open access journal from MDPI · 2026Article
- Genotyping by sequencing reveals a chromosome A04 QTL governing whitefly resistance in upland cotton.Scientific reports · 2025Article
- Chromosome-level genome assembly of a doubled haploid brook trout (Salvelinus fontinalis).G3 (Bethesda, Md.) · 2025Article
- Article
- Evolution of Size-Fecundity Relationship in Medaka Fish From Different Latitudes.Molecular ecology · 2024Article
- Mapping of Adaptive Traits Enabled by a High-Density Linkage Map for Lake Trout.G3 (Bethesda, Md.) · 2020Article
- Sex-Specific Co-expression Networks and Sex-Biased Gene Expression in the Salmonid Brook CharrG3 (Bethesda, Md.) · 2019Article
- Using Linkage Maps as a Tool To Determine Patterns of Chromosome Synteny in the GenusG3 (Bethesda, Md.) · 2017Article
- Sex Chromosome Evolution, Heterochiasmy, and Physiological QTL in the Salmonid Brook CharrG3 (Bethesda, Md.) · 2017Article
- A Dense Brown Trout (G3 (Bethesda, Md.) · 2017Article
- Salmonid Chromosome Evolution as Revealed by a Novel Method for Comparing RADseq Linkage Maps.Genome biology and evolution · 2016Article
- Population size, habitat fragmentation, and the nature of adaptive variation in a stream fish.Proceedings. Biological sciences · 2014Article
- Inter individual variations of the fish skin microbiota: host genetics basis of mutualism?PloS one · 2014Article
- Multidisciplinary population monitoring when demographic data are sparse: a case study of remote trout populations.Ecology and evolution · 2013Article
- Evolutionary change driven by metal exposure as revealed by coding SNP genome scan in wild yellow perch (Perca flavescens).Ecotoxicology (London, England) · 2013Article
- Stocking impacts the expression of candidate genes and physiological condition in introgressed brook charr (Salvelinus fontinalis) populations.Evolutionary applications · 2013Article
- Network analysis highlights complex interactions between pathogen, host and commensal microbiota.PloS one · 2013Article
- Coding Gene SNP Mapping Reveals QTL Linked to Growth and Stress Response in Brook Charr (Salvelinus fontinalis).G3 (Bethesda, Md.) · 2012Article
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A linkage map of 40 linkage groups (LGs) was developed for brook charr, Salvelinus fontinalis, using an F(2) interstrain hybrid progeny (n = 171) and 256 coding gene SNP developed specifically for brook charr and validated from a large (>1000) subset of putative SNP, as well as 81 microsatellite markers. To identify quantitative trait loci (QTL) related to reproduction functions, these fish were also phenotyped at six physiological traits, including spermatozoid head diameter, sperm concentration, plasma testosterone, plasma 11-keto-testosterone, egg diameter, and plasma 17β-estradiol. Five significant QTL were detected over four LGs for egg diameter and plasma 17β-estradiol concentration in females, and sperm concentration as well as spermatozoid head diameter in males. In females, two different QTLs located on LG 11 and LG 34 were associated with the egg number, whereas one QTL was associated with plasma 17β-estradiol concentration (LG 8). Their total percent variance explained (PVE) was 26.7% and 27.6%, respectively. In males, two QTL were also detected for the sperm concentration, and their PVE were estimated at 18.58% and 14.95%, respectively. The low QTL number, associated with the high PVE, suggests that the variance in these reproductive physiological traits was either under the control of one major gene or a small number of genes. The QTL associated with sperm concentration, plasma 17β-estradiol, and egg diameter appeared to be under a dominance effect, whereas the two others were under a negative additive effect. These results show that genes underlying the phenotypic variance of these traits are under different modes of action (additive vs. dominance) and may be used to predict an increase or a decrease in their phenotypic values in subsequent generations of selective breeding. Moreover, this newly developed panel of mapped SNP located in coding gene regions will be useful for screening wild populations, especially in the context of investigating the genetic impact of massive stocking of domestic brook charr to support the angling industry throughout eastern North America.
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