Evidence map›Paper›PMID 22412162›Full record

ArticleJournal of feline medicine and surgery2012

Slowly progressive lymphohistiocytic meningoencephalomyelitis in 21 adult cats presenting with peculiar neurological signs.

Luisa De Risio, Richard Brown, Bryn Tennant, Andy Sparkes, Lara Matiasek, Alberta de Stefani, Herbert Weissenböck, Kaspar Matiasek

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Hippocampal sclerosis in feline epilepsy.Brain pathology (Zurich, Switzerland) · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Luisa De RisioNeurology/Neurosurgery Service, Centre for Small Animal Studies, Animal Health Trust, Lanwades Park, Kentford, Suffolk, UK. luisa.derisio@aht.org.uk
Richard Brown
Bryn Tennant
Andy Sparkes
Lara Matiasek
Alberta de Stefani
Herbert Weissenböck
Kaspar Matiasek
Animal Health Trust · GBScottish Agricultural Science Agency · GBUniversity of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty-one cats presented with a history of slowly progressive neurological signs characterised by a stiff extended tail, behavioural changes, and spastic and ataxic gait. All cats had outdoor access and lived in the same geographical rural area in north-east Scotland. Histological findings were consistent with lymphohistiocytic meningoencephalomyelitis. Immunohistochemistry ruled out 15 pathogens and showed a significant expression of the interferon-inducible Mx protein, suggesting an as yet unidentified infective or environmental immunogenic trigger as the possible causative agent. The late age at onset (mean 9 years), the very slow progression of clinical signs (mean 11 months) and the peculiar clinical presentation (particularly the posture of the tail) have not been reported previously in cats with lymphohistiocytic meningoencephalomyelitis.

Indexed as

Age of OnsetAnimalsCat DiseasesCatsDisease ProgressionEncephalomyelitisFemaleGait Disorders, NeurologicHistiocytosisMaleMeningoencephalitisPostureScotlandTail

Identifiers

PMID22412162
PMCPMC10822513
OpenAlexW2001125049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.