ArticleProceedings of the National Academy of Sciences of the United States of America2012
Plasmodesmata formation and cell-to-cell transport are reduced in decreased size exclusion limit 1 during embryogenesis in Arabidopsis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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30 citing papers in PubMed, 65 citations in OpenAlex.
- Glucose-TOR-PDCB signaling restricts cell-to-cell communication through callose deposition.Science advances · 2026Article
- Role of Plasmodesmata During Plant-Pathogen Interactions.The plant pathology journal · 2026Review
- Cell-to-cell connectivity: a future target for crop improvement.Journal of experimental botany · 2026Review
- Three decades of mobile RNA silencing within plants: what have we learnt?Journal of experimental botany · 2026Review
- Measuring Plasmodesmata-mediated Intercellular Trafficking Using Microparticle Bombardment in Arabidopsis and Crops.Current protocols · 2025Article
- Abscisic acid signaling regulates primary plasmodesmata density for plant cell-to-cell communication.Science advances · 2025Article
- A pectin acetyl-transferase facilitates secondary plasmodesmata formation and RNA silencing movement between plant cells.The Plant journal : for cell and molecular biology · 2025Article
- Novel insights into RabA2b intracellular localization suggest a role in plasmodesmatal function.Frontiers in plant science · 2025Article
- Integrated analysis of physiological and metabolic data uncovers essential dynamic mechanisms involved in the maturation of cigar tobacco leaves.Scientific reports · 2024Article
- Novel resources to investigate leaf plasmodesmata formation in CThe Plant journal : for cell and molecular biology · 2024Article
- Intercellular Communication during Stomatal Development with a Focus on the Role of Symplastic Connection.International journal of molecular sciences · 2023Review
- Leaf vein patterning is regulated by the aperture of plasmodesmata intercellular channels.PLoS biology · 2022Article
- Analysis of plasmodesmata permeability using cultured tobacco BY-2 cells entrapped in microfluidic chips.Journal of plant research · 2022Article
- Strategies of tolerance reflected in two North American maple genomes.The Plant journal : for cell and molecular biology · 2022Article
- High-Altitude Genetic Selection and Genome-Wide Association Analysis of Yield-Related Traits inFrontiers in plant science · 2022Article
- Cytokinins Stimulate Plasmodesmatal Transport in Leaves.Frontiers in plant science · 2021Article
- Similarities and Differences in the GFP Movement in the Zygotic and Somatic Embryos of Arabidopsis.Frontiers in plant science · 2021Article
- Article
- TOR dynamically regulates plant cell-cell transport.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- From plasmodesma geometry to effective symplasmic permeability through biophysical modelling.eLife · 2019Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
In plants, plasmodesmata (PD) serve as channels for micromolecular and macromolecular cell-to-cell transport. Based on structure, PD in immature tissues are classified into two types, simple and branched (X- and Y-shaped) or twinned. The maximum size of molecules capable of PD transport defines PD aperture, known as the PD size exclusion limit. Here we report an Arabidopsis mutation, decreased size exclusion limit1 (dse1), that exhibits reduced cell-to-cell transport of the small (524 Da) fluorescent tracer 8-hydroxypyrene-1,3,6-trisulfonic acid at the midtorpedo stage of embryogenesis. Correspondingly, the fraction of X- and Y-shaped and twinned PD was reduced in dse1 embryos compared with WT embryos at this stage, suggesting that the frequency of PD is related to transport capability. dse1 is caused by a point mutation in At4g29860 (previously termed TANMEI) at the last donor splice site of its transcript, resulting in alternative splicing in both the first intron and the last intron. AtDSE1 is a conserved eukaryotic 386-aa WD-repeat protein critical for Arabidopsis morphogenesis and reproduction. Similar to its homologs in mouse, null mutants are embryo-lethal. The weak loss-of-function mutant dse1 exhibits pleiotropic phenotypes, including retarded vegetative growth, delayed flowering time, dysfunctional male and female organs, and delayed senescence. Finally, silencing of DSE1 in Nicotiana benthamiana leaves leads to reduced movement of GFP fused to tobacco mosaic virus movement protein. Thus, DSE1 is important for regulating PD transport between plant cells.
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