ArticleArchives of ophthalmology (Chicago, Ill. : 1960)2012
Projected clinical outcomes of glaucoma screening in African American individuals.
Article in Archives of ophthalmology (Chicago, Ill. : 1960), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- Evaluating a virtual reality visual fields analyzer in an urban, underserved glaucoma & glaucoma suspect patient populations to identify disparities.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT): Subanalysis of Referral to Ophthalmology.Current eye research · 2024Article
- Review
- Comparison of glaucoma patients referred by glaucoma screening versus referral from primary eye clinic.PloS one · 2019Article
- Local genetic ancestry in CDKN2B-AS1 is associated with primary open-angle glaucoma in an African American cohort extracted from de-identified electronic health records.BMC medical genomics · 2018Article
- Primary Open-Angle Glaucoma Genetics in African Americans.Current genetic medicine reports · 2017Article
- Presence and Risk Factors for Glaucoma in Patients with Diabetes.Current diabetes reports · 2016Review
- The Philadelphia Glaucoma Detection and Treatment Project: Detection Rates and Initial Management.Ophthalmology · 2016Article
- Extracting Primary Open-Angle Glaucoma from Electronic Medical Records for Genetic Association Studies.PloS one · 2015Article
- A comparative effectiveness analysis of visual field outcomes after projected glaucoma screening using SD-OCT in African American communities.Investigative ophthalmology & visual science · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo project the clinical impact of routine glaucoma screening on visual outcomes in middle-aged African American individuals and help guide glaucoma screening policy.
methodsUsing data from the Eye Diseases Prevalence Research Group and Baltimore Eye Study, we developed a microsimulation model to project visual outcomes in African American individuals screened for glaucoma under a national screening policy using frequency-doubling technology. We projected the impact of universal screening on glaucoma-related visual impairment (acuity worse than 20/40 but better than 20/200 in the better-seeing eye) and blindness (acuity 20/200 or worse in the better-seeing eye). The diagnostic characteristics of frequency-doubling technology and the hazard ratio for glaucoma progression in treated patients were informed by meta-analyses of randomized controlled trials.
resultsImplementation of a national glaucoma screening policy for a cohort of African American individuals between the ages of 50 and 59 years without known glaucoma would reduce the lifetime prevalence of undiagnosed glaucoma from 50% to 27%, the prevalence of glaucoma-related visual impairment from 4.6% to 4.4% (4.1% relative decrease), and the prevalence of glaucoma-related blindness from 6.1% to 5.6% (7.1% relative decrease). We project the cost of the program to be $80 per screened individual, considering only the cost of frequency-doubling technology and confirmatory eye examinations. The number needed to screen to diagnose 1 person with glaucoma is 58. The number needed to screen to prevent 1 person from developing visual impairment is 875.
conclusionsRoutine glaucoma screening for middle-aged African American individuals is potentially clinically effective but its impact on visual impairment and blindness may be modest. However, we did not assess the impact on visual field loss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.