ArticleParasitology research2012
The potential role of Phoenix dactylifera on Eimeria papillata-induced infection in mice.
Article in Parasitology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- Nutraceuticals ofDrug design, development and therapy · 2026Review
- Toltrazuril and diclazuril: comparative evaluation of anti-coccidial drugs using a murine model.The Journal of veterinary medical science · 2022Article
- Anthelmintic activity of pomegranate peel extract (Punica granatum) and synthetic anthelmintics against gastrointestinal nematodes in cattle, sheep, goats, and buffalos: in vivo study.Parasitology research · 2021Article
- Apparent metabolizable energy value of whole date palm (Phoenix dactylifera L.) and its possible use as a feedstuff for aged laying hens.Tropical animal health and production · 2017Article
- Date Palm (Frontiers in pharmacology · 2017Article
- Anticoccidial activities of Chitosan on Eimeria papillata-infected mice.Parasitology research · 2016Article
- Immunomodulatory and antiparasitic effects of garlic extract on Eimeria vermiformis-infected mice.Parasitology research · 2015Article
- Antioxidant and anti-inflammatory activities of pomegranate (Punica granatum) on Eimeria papillata-induced infection in mice.BioMed research international · 2015Article
- Towards identifying novel anti-Eimeria agents: trace elements, vitamins, and plant-based natural products.Parasitology research · 2014Review
- Antiparasitic effect of wild rue (Peganum harmala L.) against experimentally induced coccidiosis in broiler chicks.Parasitology research · 2014Article
- Anti-coccidial, anthelmintic and antioxidant activities of pomegranate (Punica granatum) peel extract.Parasitology research · 2013Article
- Protective effect of Azadirachta indica extract against Eimeria papillata-induced coccidiosis.Parasitology research · 2013Article
- Anticoccidial activity of traditional Chinese herbal Dichroa febrifuga Lour. extract against Eimeria tenella infection in chickens.Parasitology research · 2012Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coccidiosis is a common infectious disease in poultry causing major economic losses. Here, we investigated the effect of Khodary date fruit aqueous extract (4 ml/kg) on the outcome of coccidiosis caused by Eimeria papillata in Swiss Albino mice. Date fruit extract was able to decrease the intracellular development by lowering the faecal output of E. papillata oocysts from 8.7 ± 0.5 × 10(3) to 6.6 ± 0.4 × 10(3) oocysts per gram faeces. Also, date extract caused a great diminish in body weight of infected mice from 19.3 to 3.2 %. The number of parasitic stages in the intestinal villi of the infected mice was reduced to about 52 % after treatment with date extract. The infection was associated with marked histopathological lesions of the murine jejunum in the form of inflammation, vacuolation of the epithelium, and destruction of some villi. Also, the number of goblet cells within the infected villi was significantly lowered (P ≤ 0.05). These changes lead to an oxidative damage of the infected tissue. Moreover, infection induced a disturbance in both protein and carbohydrate content in the infected mice. Treatment of mice with date extract could improve the above-studied parameters. On the basis of the above results it can be hypothesized that date fruit can protect against coccidiosis-induced infection, this hypothesis can be revealed by the anti-inflammatory activity of date protecting host tissue from injuries induced by the parasite, and hence it is recommended to be used as an excellent food additive.
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