ArticleJournal of neurovirology2012
An initial screening for HIV-associated neurocognitive disorders of HIV-1 infected patients in China.
Article in Journal of neurovirology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Impact of Cannabis Use on Cognition in People with HIV: Evidence of Function-Dependent Effects and Mechanisms from Clinical and Preclinical Studies.Current HIV/AIDS reports · 2024Pooled it
- The Mental Health of People Living with HIV in China, 1998-2014: A Systematic Review.PloS one · 2016Pooled it
- A systematic review of the screening accuracy of the HIV Dementia Scale and International HIV Dementia Scale.PloS one · 2013Pooled it
- A longitudinal study of the brain structure network changes in HIV patients with ANI: combined VBM with SCN.Frontiers in neurology · 2024Article
- Brief Report: Sex Differences in the Association Between Cerebrovascular Function and Cognitive Health in People Living With HIV in Urban China.Journal of acquired immune deficiency syndromes (1999) · 2023Article
- Early prediction of putamen imaging features in HIV-associated neurocognitive impairment syndrome.BMC neurology · 2021Article
- Article
- HIV-associated neurocognitive disorders at Moi teaching and referral hospital, Eldoret, Kenya.BMC neurology · 2020Article
- Antiretroviral therapy improves neurocognitive impairment in people living with HIV? A meta-analysis.International journal of nursing sciences · 2020Review
- HIV-associated cognitive performance and psychomotor impairment in a Thai cohort on long-term cART.Journal of virus eradication · 2018Article
- Comparison of two screening tests for HIV-Associated Neurocognitive Disorder suspected Japanese patients with respect to cART usage.PloS one · 2018Article
- Neurosyphilis Increases Human Immunodeficiency Virus (HIV)-associated Central Nervous System Inflammation but Does Not Explain Cognitive Impairment in HIV-infected Individuals With Syphilis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Article
- Prevalence and Correlates of HIV-Associated Neurocognitive Disorders (HAND) in Northwestern Nigeria.Neurology research international · 2015Article
- Discordant patterns of tissue-specific genetic characteristics in the HIV-1 env gene from HIV-associated neurocognitive disorder (HAND) and non-HAND patients.Journal of neurovirology · 2014Article
- Neurology and the Global HIV Epidemic.Seminars in neurology · 2014Review
- Effect of HIV clade differences on the onset and severity of HIV-associated neurocognitive disorders.Journal of neurovirology · 2013Review
- High levels of divergent HIV-1 quasispecies in patients with neurological opportunistic infections in China.Journal of neurovirology · 2013Article
- Trail Making Test A improves performance characteristics of the International HIV Dementia Scale to identify symptomatic HAND.Journal of neurovirology · 2013Article
- Discordant genotypic resistance and HIV-1 genetic diversity from paired plasma and cerebrospinal fluid samples in Chinese settings.Journal of neurovirology · 2013Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
HIV-associated neurocognitive disorders (HAND), characterized by cognitive, motor, and behavioral abnormalities, are common among people living with HIV and AIDS. In combined antiretroviral therapy era in Western countries, nearly 40% of HIV-infected patients continue to suffer from HAND, mainly with mild or asymptomatic cognitive impairment. However, the prevalence and the clinical features of HAND in China are still not well known. In this study, a multi-center cross-sectional study was performed to determine the prevalence and clinical features of HAND in 134 HIV-1 infected patients in China. The International HIV Dementia Scale and a neuropsychological test battery were administered for screening and diagnosis HAND. Subjective complaints, CD4 count and viral loads in both blood plasma and cerebrospinal fluid were correlated with diagnosis of HAND. The results showed that the prevalence of HAND was approximately 37% in these patients. CD4 counts at time of sampling were significant lower in the HAND group than in the non-HAND group. But the distribution of the HAND severity did not differ by CD4 count or viral load. The presence of HAND was associated with cognitive and behavior disorder complaints (4.9- and 4.1-fold higher than those without HAND, respectively). The present data suggest that CD4 count and viral load cannot predict the severity of HAND, although the prevalence of HAND is similar to previous report in these patients. Cognitive and behavioral disorder is major complaint rather than cognitive and motor impairment. A larger prospective study is needed to obtain better estimates of HAND in China.
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