Evidence map›Paper›PMID 22408345›Full record

ReviewWorld journal of gastroenterology2012

Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis.

Eduardo Garcia Vilela, Henrique Osvaldo da Gama Torres, Fabiana Paiva Martins, Maria de Lourdes de Abreu Ferrari, Marcella Menezes Andrade, Aloísio Sales da Cunha

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The histopathological approach to inflammatory bowel disease: a practice guide.Virchows Archiv : an international journal of pathology · 2014
    Guideline
  2. Article
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  11. Lactobacillus plantarum strains attenuated DSS-induced colitis in mice by modulating the gut microbiota and immune response.International microbiology : the official journal of the Spanish Society for Microbiology · 2022
    Article
  12. Article
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  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Antiarthritic Activity ofOpen access Macedonian journal of medical sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eduardo Garcia VilelaInternal Medicine Department, Faculty of Medicine, Federal University of Minas Gerais, Minas Gerais 30130-100, Brazil. evilela@medicina.ufmg.br
Henrique Osvaldo da Gama Torres
Fabiana Paiva Martins
Maria de Lourdes de Abreu Ferrari
Marcella Menezes Andrade
Aloísio Sales da Cunha

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crohn's disease and ulcerative colitis evolve with a relapsing and remitting course. Determination of inflammatory state is crucial for the assessment of disease activity and for tailoring therapy. However, no simple diagnostic test for monitoring intestinal inflammation is available. Noninvasive markers give only indirect assessments of disease activity. Histopathological or endoscopical examinations accurately assess inflammatory activity, but they are invasive, time consuming and expensive and therefore are unsuitable for routine use. Imaging procedures are not applicable for ulcerative colitis. The usefulness of ultrasound and Doppler imaging in assessing disease activity is still a matter of discussion for Crohn's disease, and an increased interest in computed tomography enterograph (CTE) has been seen, mainly because it can delineate the extent and severity of bowel wall inflammation, besides detecting extraluminal findings. Until now, the available data concerning the accuracy of magnetic resonance enterography in detecting disease activity is less than CTE. Due to this, clinical activity indices are still commonly used for both diseases.

Indexed as

BiomarkersColitis, UlcerativeCrohn DiseaseEndoscopyHumansInflammationIntestinesMagnetic Resonance ImagingSeverity of Illness IndexTomography, X-Ray ComputedBiomarkersCrohn’s diseaseDiagnostic testInflammatory bowel diseaseInflammatory markersTherapyUlcerative colitis

Identifiers

PMID22408345
PMCPMC3297045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.