Trial reportEuropean journal of nutrition2013
Carbon and nitrogen isotopic ratios of urine and faeces as novel nutritional biomarkers of meat and fish intake.
Trial report in European journal of nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 59 citations in OpenAlex.
- The Breath Carbon Isotope Ratio Reflects Short-term Added-Sugar Intake in a Dose-Response, Crossover Feeding Study of 12 Healthy Adults.The Journal of nutrition · 2021Trial
- Associations of plasma, RBCs, and hair carbon and nitrogen isotope ratios with fish, meat, and sugar-sweetened beverage intake in a 12-wk inpatient feeding study.The American journal of clinical nutrition · 2019Trial
- Identification of Synthetic Urine by Analysis of Stable Carbon and Nitrogen Isotope Ratios and Comparison to Established GC-MS/MS and LC-MS/MS Analysis.Drug testing and analysis · 2026Article
- Carbon and Nitrogen Stable Isotopic Discrimination Factors Between Diet and Feces in Wild Giant Pandas.Biology · 2026Article
- Seeing Roman life through water: Exploring Pompeii's public baths via carbonate deposits.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Urine Stable Isotope Ratios Are Associated with Proportional Intakes of Animal Protein and Added Sugars in a 15-Day Controlled Feeding Study.The Journal of nutrition · 2025Article
- Is What Comes out the Same as What Goes in? A Preliminary Investigation of the Isotopic Impacts of Digestion by Red-Tailed Hawks (Ecology and evolution · 2025Article
- Dogs in Lithuania from the 12th to 18th C AD: Diet and Health According to Stable Isotope, Zooarchaeological, and Historical Data.Animals : an open access journal from MDPI · 2024Article
- Discerning animal-sourced food in diet using isotope analysis of human scalp hair and fingernails.European journal of nutrition · 2024Article
- Article
- Observational
- Human and dog Bayesian dietary mixing models using bone collagen stable isotope ratios from ancestral Iroquoian sites in southern Ontario.Scientific reports · 2023Article
- The association between carbon and nitrogen stable isotope ratios of human hair and hypertension.Clinical hypertension · 2023Article
- A new era of isotope ecology: Nitrogen isotope ratio of amino acids as an approach for unraveling modern and ancient food web.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2023Article
- Collection of biospecimens from parent-child dyads in a community garden-based nutrition intervention: protocol and feasibility.BMC nutrition · 2022Article
- Organic geochemistry and mineralogy suggest anthropogenic impact in speleothem chemistry from volcanic show caves of the Galapagos.iScience · 2022Article
- Integrative analysis of DNA, macroscopic remains and stable isotopes of dog coprolites to reconstruct community diet.Scientific reports · 2021Article
- Effect of Organic Food Intake on Nitrogen Stable Isotopes.Nutrients · 2020Article
- Biomarkers of meat and seafood intake: an extensive literature review.Genes & nutrition · 2019Review
- Serum Nitrogen and Carbon Stable Isotope Ratios Meet Biomarker Criteria for Fish and Animal Protein Intake in a Controlled Feeding Study of a Women's Health Initiative Cohort.The Journal of nutrition · 2018Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
purposeMeat and fish consumption are associated with changes in the risk of chronic diseases. Intake is mainly assessed using self-reporting, as no true quantitative nutritional biomarker is available. The measurement of plasma fatty acids, often used as an alternative, is expensive and time-consuming. As meat and fish differ in their stable isotope ratios, δ(13)C and δ(15)N have been proposed as biomarkers. However, they have never been investigated in controlled human dietary intervention studies.
objectiveIn a short-term feeding study, we investigated the suitability of δ(13)C and δ(15)N in blood, urine and faeces as biomarkers of meat and fish intake.
methodsThe dietary intervention study (n = 14) followed a randomised cross-over design with three eight-day dietary periods (meat, fish and half-meat-half-fish). In addition, 4 participants completed a vegetarian control period. At the end of each period, 24-h urine, fasting venous blood and faeces were collected and their δ(13)C and δ(15)N analysed.
resultsThere was a significant difference between diets in isotope ratios in faeces and urine samples, but not in blood samples (Kruskal-Wallis test, p < 0.0001). In pairwise comparisons, δ(13)C and δ(15)N were significantly higher in urine and faecal samples following a fish diet when compared with all other diets, and significantly lower following a vegetarian diet. There was no significant difference in isotope ratio between meat and half-meat-half-fish diets for blood, urine or faecal samples.
conclusionsThe results of this study show that urinary and faecal δ(13)C and δ(15)N are suitable candidate biomarkers for short-term meat and fish intake.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.