ArticleNucleic acids research2012
Novel insight into the non-coding repertoire through deep sequencing analysis.
Article in Nucleic acids research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- MicroRNAs Regulating Autophagy in Neurodegeneration.Advances in experimental medicine and biology · 2021Article
- A comprehensive annotation and differential expression analysis of short and long non-coding RNAs in 16 bat genomes.NAR genomics and bioinformatics · 2020Article
- Temporal dynamics in meta longitudinal RNA-Seq data.Scientific reports · 2019Article
- HIV-1 infection increases microRNAs that inhibit Dicer1, HRB and HIV-EP2, thereby reducing viral replication.PloS one · 2019Article
- Long noncoding RNA FOXD3-AS1 regulates oxidative stress-induced apoptosisFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2017Article
- MicroRNA-mediated regulation of p21 and TASK1 cellular restriction factors enhances HIV-1 infection.Journal of cell science · 2015Article
- Computational Approaches for the Analysis of ncRNA through Deep Sequencing Techniques.Frontiers in bioengineering and biotechnology · 2015Review
- Changing genetic paradigms: creating next-generation genetic databases as tools to understand the emerging complexities of genotype/phenotype relationships.Human genomics · 2014Article
- The involvement of microRNAs in major depression, suicidal behavior, and related disorders: a focus on miR-185 and miR-491-3p.Cellular and molecular neurobiology · 2014Review
- iMir: an integrated pipeline for high-throughput analysis of small non-coding RNA data obtained by smallRNA-Seq.BMC bioinformatics · 2013Article
- Bioinformatics of Cancer ncRNA in High Throughput Sequencing: Present State and Challenges.Frontiers in genetics · 2012Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-coding RNAs (ncRNA) account for a large portion of the transcribed genomic output. This diverse family of untranslated RNA molecules play a crucial role in cellular function. The use of 'deep sequencing' technology (also known as 'next generation sequencing') to infer transcript expression levels in general, and ncRNA specifically, is becoming increasingly common in molecular and clinical laboratories. We developed a software termed 'RandA' (which stands for ncRNA Read-and-Analyze) that performs comprehensive ncRNA profiling and differential expression analysis on deep sequencing generated data through a graphical user interface running on a local personal computer. Using RandA, we reveal the complexity of the ncRNA repertoire in a given cell population. We further demonstrate the relevance of such an extensive ncRNA analysis by elucidating a multitude of characterizing features in pathogen infected mammalian cells. RandA is available for download at http://ibis.tau.ac.il/RandA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.