ArticleNature neuroscience2012
Dense representation of natural odorants in the mouse olfactory bulb.
Article in Nature neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- Adult-neurogenesis allows for representational stability and flexibility in early olfactory system.eLife · 2026Article
- Odor identity decoding by mitral/tufted cells in the olfactory bulb from large-scale pooled datasets.iScience · 2026Article
- Zic3 enables bimodal regulation of tyrosine hydroxylase expression in olfactory bulb and midbrain-derived neurons.Cell death discovery · 2025Article
- Recalibrating Olfactory Neuroscience to the Range of Naturally Occurring Odor Concentrations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Dense and Persistent Odor Representations in the Olfactory Bulb of Awake Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Imaging different cell populations in the mouse olfactory bulb using the genetically encoded voltage indicator ArcLight.Neurophotonics · 2024Review
- Odor encoding by signals in the olfactory bulb.Journal of neurophysiology · 2023Article
- Olfactory Sensing and Navigation in Turbulent Environments.Annual review of condensed matter physics · 2022Article
- State-dependent olfactory processing in freely behaving mice.Cell reports · 2022Article
- Spatially Distributed Representation of Taste Quality in the Gustatory Insular Cortex of Behaving Mice.Current biology : CB · 2021Article
- Stimulus Driven Functional Transformations in the Early Olfactory System.Frontiers in cellular neuroscience · 2021Article
- Predicting brain organization with a computational model: 50-year perspective on lateral inhibition and oscillatory gating by dendrodendritic synapses.Journal of neurophysiology · 2020Review
- Complex neural representation of odour information in the olfactory bulb.Acta physiologica (Oxford, England) · 2020Review
- The self-organized learning of noisy environmental stimuli requires distinct phases of plasticity.Network neuroscience (Cambridge, Mass.) · 2020Article
- Similarity and Strength of Glomerular Odor Representations Define a Neural Metric of Sniff-Invariant Discrimination Time.Cell reports · 2019Article
- Diverse tuning underlies sparse activity in layer 2/3 vibrissal cortex of awake mice.The Journal of physiology · 2019Article
- Parallel odor processing by mitral and middle tufted cells in the olfactory bulb.Scientific reports · 2018Article
- Antagonism in olfactory receptor neurons and its implications for the perception of odor mixtures.eLife · 2018Article
- Two-Photon Functional Imaging of the Auditory Cortex in Behaving Mice: From Neural Networks to Single Spines.Frontiers in neural circuits · 2018Article
- IGF1-Dependent Synaptic Plasticity of Mitral Cells in Olfactory Memory during Social Learning.Neuron · 2017Article
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5 authors.
Funding
Abstract
In mammals, odorant molecules are thought to activate only a few glomeruli, leading to the hypothesis that odor representation in the olfactory bulb is sparse. However, the studies supporting this model used anesthetized animals or monomolecular odorants at limited concentration ranges. Using optical imaging and two-photon microscopy, we found that natural odorants at their native concentrations could elicit dense representations in the olfactory bulb. Both anesthesia and odorant concentration were found to modulate the representation density of natural odorants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.