Evidence map›Paper›PMID 22406539›Full record

ReviewJournal of structural biology2012

Integrated control of axonemal dynein AAA(+) motors.

Stephen M King

Open access · greenAbstract readReview
In one paragraph

Review in Journal of structural biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

  1. Bi-allelic variants inHuman reproduction open · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Aquatic models of human ciliary diseases.Genesis (New York, N.Y. : 2000) · 2021
    Review
  7. Review
  8. An integrated omics approach to investigate summer mortality of New Zealand Greenshell™ mussels.Metabolomics : Official journal of the Metabolomic Society · 2020
    Article
  9. Review
  10. Article
  11. Review
  12. Axonemal Dynein Arms.Cold Spring Harbor perspectives in biology · 2016
    Review
  13. Article
  14. Two-headed outer- and inner-arm dyneins ofBiochemistry and biophysics reports · 2015
    Article
  15. Article
  16. Article
  17. Review
  18. Functions and mechanics of dynein motor proteins.Nature reviews. Molecular cell biology · 2013
    Review
  19. Article
  20. Big steps toward understanding dynein.The Journal of cell biology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stephen M KingDepartment of Molecular, Microbial and Structural Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-3305, USA. king@neuron.uchc.edu
UConn Health · US

Funding

MOLECULAR ANALYSIS OF FLAGELLAR DYNEIN FUNCTIONR01GM051293 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI KING, STEPHEN M · 1995 to 2020
$6.9M
NIGMS NIH HHS GM051293NIGMS NIH HHS R01 GM051293
6 · The paper itself

Abstract

Axonemal dyneins are AAA(+) enzymes that convert ATP hydrolysis to mechanical work. This leads to the sliding of doublet microtubules with respect to each other and ultimately the generation of ciliary/flagellar beating. However, in order for useful work to be generated, the action of individual dynein motors must be precisely controlled. In addition, cells modulate the motility of these organelles through a variety of second messenger systems and these signals too must be integrated by the dynein motors to yield an appropriate output. This review describes the current status of efforts to understand dynein control mechanisms and their connectivity focusing mainly on studies of the outer dynein arm from axonemes of the unicellular biflagellate green alga Chlamydomonas.

Indexed as

Axonemal DyneinsChlamydomonasDyneinsAxonemal DyneinsDyneins

Identifiers

PMID22406539
PMCPMC3378790
OpenAlexW2006770111

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.