Evidence map›Paper›PMID 22406230›Full record

ArticleJournal of the American Academy of Dermatology2012

Sun damage in ultraviolet photographs correlates with phenotypic melanoma risk factors in 12-year-old children.

Ryan G Gamble, Nancy L Asdigian, Jenny Aalborg, Victoria Gonzalez, Neil F Box, Laura S Huff, Anna E Barón, Joseph G Morelli, Stefan T Mokrohisky, Lori A Crane and 1 more

Abstract read
In one paragraph

Article in Journal of the American Academy of Dermatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Increasing Skin Cancer Prevention in Young Adults: the Cumulative Impact of Personalized UV Photography and MC1R Genetic Testing.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023
    Trial
  2. Trial
  3. Article
  4. Tailored visuals, implementation interventions, and sun safe behavior: A longitudinal message experiment.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Trihydroxybenzoic acid glucoside as a global skin color modulator and photo-protectant.Clinical, cosmetic and investigational dermatology · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ryan G GambleDepartment of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Nancy L Asdigian
Jenny Aalborg
Victoria Gonzalez
Neil F Box
Laura S Huff
Anna E Barón
Joseph G Morelli
Stefan T Mokrohisky
Lori A Crane
Robert P Dellavalle
University of Colorado Anschutz Medical Campus · USColorado School of Public Health · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
SKIN CANCER PREVENTION IN A PEDIATRIC POPULATIONR01CA074592 · NCI · UNIVERSITY OF COLORADO DENVER · PI BOX, NEIL FREDERICK, CRANE, LORI A. · 1997 to 2014
$5.2M
NCI NIH HHS P30 CA046934NCI NIH HHS P30CA046934NCI NIH HHS R01 CA074592
6 · The paper itself

Abstract

backgroundUltraviolet (UV) photography has been used to motivate sun safety in behavioral interventions. The relationship between sun damage shown in UV photographs and melanoma risk has not been systematically investigated.

objectiveTo examine the relationship between severity of sun damage in UV photographs and phenotypic melanoma risk factors in children.

methodsUV, standard visible and cross-polarized photographs were recorded for 585 children. Computer software quantified sun damage. Full-body nevus counts, skin color by colorimetry, facial freckling, hair and eye color were collected in skin examinations. Demographic data were collected in telephone interviews of parents.

resultsAmong 12-year-old children, sun damage shown in UV photographs correlated with phenotypic melanoma risk factors. Sun damage was greatest for children who were non-Hispanic white and those who had red hair, blue eyes, increased facial freckling, light skin and greater number of nevi (all P values < .001). Results were similar for standard visible and cross-polarized photographs. Freckling was the strongest predictor of sun damage in visible and UV photographs. All other phenotypic melanoma risk factors were also predictors for the UV photographs. LIMITATIONS: Differences in software algorithms used to score the photographs could produce different results.

conclusionUV photographs portray more sun damage in children with higher risk for melanoma based on phenotype. Therefore sun protection interventions targeting those with greater sun damage on UV photographs will target those at higher melanoma risk. This study establishes reference ranges dermatologists can use to assess sun damage in their pediatric patients.

Indexed as

AlgorithmsChildCohort StudiesFaceFemaleHumansImage Processing, Computer-AssistedMaleMelanomaMelanosisNevusPhenotypePhotographyRisk FactorsSeverity of Illness IndexSkin Aging

Identifiers

PMID22406230
PMCPMC3888435
OpenAlexW2095940270

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.