ArticleBMC health services research2012
The effects of oral clefts on hospital use throughout the lifespan.
Article in BMC health services research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- High dosage folic acid supplementation, oral cleft recurrence and fetal growth.International journal of environmental research and public health · 2013Trial
- Cleft Lip and Palate: Overview of Causes, Surgical Repair, and Treatment Approaches: A Narrative Review.World journal of plastic surgery · 2025Review
- Academic outcomes of children with orofacial clefts: A review of the literature and recommendations for future research.Oral diseases · 2022Review
- Article
- Genetic variants in S-adenosyl-methionine synthesis pathway and nonsyndromic cleft lip with or without cleft palate in Chile.Pediatric research · 2021Article
- State-Mandated Coverage of Cleft Lip and Cleft Palate Treatment.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2020Review
- Article
- Maternal underweight and obesity and risk of orofacial clefts in a large international consortium of population-based studies.International journal of epidemiology · 2017Article
- Passive Smoke Exposure as a Risk Factor for Oral Clefts-A Large International Population-Based Study.American journal of epidemiology · 2016Article
- Psychiatric Diagnoses in Individuals with Non-Syndromic Oral Clefts: A Danish Population-Based Cohort Study.PloS one · 2016Article
- Psychosocial well-being of parents of children with oral clefts.Child: care, health and development · 2016Article
- Description of total population hospital admissions for cleft lip and/or palate in Australia.BMC oral health · 2015Article
- Long-term effects of oral clefts on health care utilization: a sibling comparison.The European journal of health economics : HEPAC : health economics in prevention and care · 2015Article
- Analysis of MTHFR Gene C.677C>T and C.1298A>C Polymorphisms in Iranian Patients with Non-Syndromic Cleft Lip and Palate.Iranian journal of public health · 2014Article
- Comparing the Visual Analogue Scale and the Pediatric Quality of Life Inventory for measuring health-related quality of life in children with oral clefts.International journal of environmental research and public health · 2014Article
- Oral cleft recurrence risk and subsequent maternal fertility preferences and behavior in Brazil.Birth defects research. Part A, Clinical and molecular teratology · 2014Article
- Hospital care of children with a cleft in England.Archives of disease in childhood · 2013Article
- X-linked markers in the Duchenne muscular dystrophy gene associated with oral clefts.European journal of oral sciences · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundOral clefts are one of the most common birth defects worldwide. They require multiple healthcare interventions and add significant burden on the health and quality of life of affected individuals. However, not much is known about the long term effects of oral clefts on health and healthcare use of affected individuals. In this study, we evaluate the effects of oral clefts on hospital use throughout the lifespan.
methodsWe estimate two-part regression models for hospital admission and length of stay for several age groups up to 68 years of age. The study employs unique secondary population-based data from several administrative inpatient, civil registration, demographic and labor market databases for 7,670 individuals born with oral clefts between 1936 and 2002 in Denmark, and 220,113 individuals without oral clefts from a 5% random sample of the total birth population from 1936 to 2002.
resultsOral clefts significantly increase hospital use for most ages below 60 years by up to 233% for children ages 0-10 years and 16% for middle age adults. The more severe cleft forms (cleft lip with palate) have significantly larger effects on hospitalizations than less severe forms.
conclusionsThe results suggest that individuals with oral clefts have higher hospitalization risks than the general population throughout most of the lifespan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.