Evidence map›Paper›PMID 22405177›Full record

ReviewJournal of Crohn's & colitis2012

Results of the 2nd scientific workshop of the ECCO (III): basic mechanisms of intestinal healing.

Florian Rieder, Thomas Karrasch, Shomron Ben-Horin, Anja Schirbel, Robert Ehehalt, Jan Wehkamp, Colin de Haar, Dominique Velin, Giovanni Latella, Franco Scaldaferri and 3 more

RetractedErratum issued Registry-linked trialOpen access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of Crohn's & colitis, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. It is linked to trial NCT03885713 (Identification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease by Proteomic and Mass Cytometry Approaches), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03885713 phase4completednot on this mapstarted 2019, after this paper: background citation

Identification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease by Proteomic and Mass Cytometry Approaches

TypeinterventionalSponsorFundación de Investigación Biomédica - Hospital Universitario de La PrincesaRan2019 to 2024Enrolled180ConditionsInflammatory Bowel Diseases, Crohn Disease, Ulcerative ColitisArmsInfliximab or adalimumab or golimumab or vedolizumab or ustekinumab or tofacitinib
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. The Pathogenesis of Inflammatory Bowel Diseases.The Surgical clinics of North America · 2025
    Review
  5. Article
  6. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Gastroenterology research and practice · 2020
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

  • Expression of concern · 2022-01-24Civil Proceedings · Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Legal Reasons and/or Threats · · See also: https://doi.org/10.1093/ecco-jcc/jjab225 Journal was previously published by Elsevier until 2015.
  • Commented on by
  • Erratum issued
5 · Who and what money

Authors and funding

13 authors at 13 institutions in 7 countries.

Florian RiederDepartment of Gastroenterology & Hepatology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, USA. riederf@ccf.org
Thomas Karrasch
Shomron Ben-Horin
Anja Schirbel
Robert Ehehalt
Jan Wehkamp
Colin de Haar
Dominique Velin
Giovanni Latella
Franco Scaldaferri
Gerhard Rogler
Peter Higgins
Miquel Sans
Agostino Gemelli University Polyclinic · ITCharité - Universitätsmedizin Berlin · DECleveland Clinic Lerner College of Medicine · USErasmus University Rotterdam · NLHeidelberg University · DEHospital Clínic de Barcelona · ESSheba Medical Center · ILUniversity of L'Aquila · ITUniversity of Lausanne · CHUniversity of Michigan–Ann Arbor · USUniversity of Regensburg · DEUniversity of Tübingen · DEUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The second scientific workshop of the European Crohn's and Colitis Organization (ECCO) focused on the relevance of intestinal healing for the disease course of inflammatory bowel disease (IBD). The objective was to better understand basic mechanisms, markers for disease prediction, detection and monitoring of intestinal healing, impact of intestinal healing on the disease course of IBD as well as therapeutic strategies. The results of this workshop are presented in four separate manuscripts. This section describes basic mechanisms of intestinal healing, identifies open questions in the field and provides a framework for future studies.

Indexed as

Adrenal Cortex HormonesAnti-Bacterial AgentsAntibodies, MonoclonalAnti-Inflammatory Agents, Non-SteroidalAzathioprineButyric AcidColitis, UlcerativeCrohn DiseaseCyclosporineDefensinsExtracellular MatrixHumansImmunosuppressive AgentsInfliximabIntestinal MucosaLeptinAdrenal Cortex HormonesAnti-Bacterial AgentsAntibodies, MonoclonalAnti-Inflammatory Agents, Non-SteroidalAzathioprineButyric AcidCyclosporineDefensinsImmunosuppressive AgentsInfliximabLeptinMatrix MetalloproteinasesMesalamineReactive Nitrogen SpeciesReactive Oxygen SpeciesSulfasalazineTumor Necrosis Factor-alpha

Identifiers

PMID22405177
OpenAlexW2063628403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.