Evidence map›Paper›PMID 22404858›Full record

ArticleEnvironmental health : a global access science source2012

Particulate matter exposure during pregnancy is associated with birth weight, but not gestational age, 1962-1992: a cohort study.

Mark S Pearce, Svetlana V Glinianaia, Rakesh Ghosh, Judith Rankin, Steven Rushton, Martin Charlton, Louise Parker, Tanja Pless-Mulloli

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Industrial air pollution and low birth weight: a case-control study in Texas, USA.Environmental science and pollution research international · 2018
    Article
  4. The health burden of pollution: the impact of prenatal exposure to air pollutants.International journal of chronic obstructive pulmonary disease · 2015
    Review
  5. Review
  6. 1991 Gulf War exposures and adverse birth outcomes.U.S. Army Medical Department journal
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Mark S PearceInstitute of Health and Society, Newcastle University, Newcastle upon Tyne, England, UK. mark.pearce@ncl.ac.uk
Svetlana V Glinianaia
Rakesh Ghosh
Judith Rankin
Steven Rushton
Martin Charlton
Louise Parker
Tanja Pless-Mulloli
Newcastle University · GBDalhousie University · CANational University of Ireland, Maynooth · IEUniversity of California, Davis · US

Funding

Wellcome Trust 072465/Z/03/Z
6 · The paper itself

Abstract

backgroundExposure to air pollutants is suggested to adversely affect fetal growth, but the evidence remains inconsistent in relation to specific outcomes and exposure windows.

methodsUsing birth records from the two major maternity hospitals in Newcastle upon Tyne in northern England between 1961 and 1992, we constructed a database of all births to mothers resident within the city. Weekly black smoke exposure levels from routine data recorded at 20 air pollution monitoring stations were obtained and individual exposures were estimated via a two-stage modeling strategy, incorporating temporally and spatially varying covariates. Regression analyses, including 88,679 births, assessed potential associations between exposure to black smoke and birth weight, gestational age and birth weight standardized for gestational age and sex.

resultsSignificant associations were seen between black smoke and both standardized and unstandardized birth weight, but not for gestational age when adjusted for potential confounders. Not all associations were linear. For an increase in whole pregnancy black smoke exposure, from the 1(st) (7.4 μg/m(3)) to the 25(th) (17.2 μg/m(3)), 50(th) (33.8 μg/m(3)), 75(th) (108.3 μg/m(3)), and 90(th) (180.8 μg/m(3)) percentiles, the adjusted estimated decreases in birth weight were 33 g (SE 1.05), 62 g (1.63), 98 g (2.26) and 109 g (2.44) respectively. A significant interaction was observed between socio-economic deprivation and black smoke on both standardized and unstandardized birth weight with increasing effects of black smoke in reducing birth weight seen with increasing socio-economic disadvantage.

conclusionsThe findings of this study progress the hypothesis that the association between black smoke and birth weight may be mediated through intrauterine growth restriction. The associations between black smoke and birth weight were of the same order of magnitude as those reported for passive smoking. These findings add to the growing evidence of the harmful effects of air pollution on birth outcomes.

Indexed as

Birth WeightEnvironmental ExposureGestational AgeAdolescentAdultAir PollutantsCitiesCohort StudiesEnglandFemaleHumansInfant, NewbornMaleMaternal ExposureMiddle AgedParticulate MatterAir PollutantsParticulate MatterSmoke

Identifiers

PMID22404858
PMCPMC3324390
OpenAlexW2107578904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.