SynthesisHPB : the official journal of the International Hepato Pancreato Biliary Association2012
Meta-analysis of one- vs. two-stage laparoscopic/endoscopic management of common bile duct stones.
Synthesis in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04213092 ("Single Setting ERCP and Laparoscopic Cholecystectomy is a Safe Procedure in Patients With Cholecysto-Choledocholithiasis), which is not on this map. Cited by 42 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
"Single Setting ERCP and Laparoscopic Cholecystectomy is a Safe Procedure in Patients With Cholecysto-Choledocholithiasis: A Prospective Study in a Peripheral-Level Hospital"
Who cites it
42 citing papers in PubMed, 5 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Pooled it
- Laparoscopic-endoscopic rendezvous versus preoperative endoscopic sphincterotomy in people undergoing laparoscopic cholecystectomy for stones in the gallbladder and bile duct.The Cochrane database of systematic reviews · 2018Pooled it
- Pooled it
- Evidence-based clinical practice guidelines for cholelithiasis 2016.Journal of gastroenterology · 2017Guideline
- Transcystic or transductal stone extraction during single-stage treatment of choledochocystolithiasis: a systematic review.World journal of surgery · 2014Pooled it
- Review
- Intraoperative Cholangiogram Interpretation for Laparoscopic Transcystic Bile Duct Exploration: Is Concurrence Possible?Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025Article
- Laparoendoscopic Rendezvous: An Effective and Safe Approach in the Management of Cholecysto-Choledocholithiasis in Selected Patients.Journal of clinical medicine · 2025Article
- Efficacy of neoadjuvant therapy and lymph node dissection in advanced gallbladder cancer without distant metastases: a SEER database analysis.Frontiers in oncology · 2024Article
- Laparoscopic common bile duct exploration with primary closure is preferred for selected elderly individuals with choledocholithiasis.Annals of gastroenterological surgery · 2023Article
- Minimally invasive management of concomitant gallstones and common bile duct stones: an updated network meta-analysis of randomized controlled trials.Surgical endoscopy · 2023Review
- Comparing One-Stage vs Two-Stage Approaches for the Management of Choledocholithiasis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Review
- One-stage approach to cholecystocholedocholithiasis treatment: a feasible surgical strategy for emergency settings and frail patients.Surgical endoscopy · 2022Article
- Destiny for Rendezvous: Is Cholecysto/Choledocholithiasis Better Treated with Dual- or Single-Step Procedures?Digestive diseases and sciences · 2022Review
- Laparo-endoscopic management of chole-choledocholithiasis: Rendezvous or intraoperative ERCP? A single tertiary care center experience.Frontiers in surgery · 2022Article
- Contemporary management of concomitant gallstones and common bile duct stones: a survey of Spanish surgeons.Surgical endoscopy · 2021Article
- Management of cholelithiasis with choledocholithiasis: Endoscopic and surgical approaches.World journal of gastroenterology · 2021Review
- Choledocholithiasis-a new clinical pathway.Translational gastroenterology and hepatology · 2021Review
- Transductal versus transcystic laparoscopic common bile duct exploration: an institutional review of over four hundred cases.Surgical endoscopy · 2021Article
- Decision analysis of minimally invasive management options for cholecysto-choledocholithiasis.Surgical endoscopy · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study is a meta-analysis of English articles comparing one-stage [laparoscopic common bile duct exploration or intra-operative endoscopic retrograde cholangiopancreatography (ERCP)] vs. two-stage (laparoscopic cholecystectomy preceded or followed by ERCP) management of common bile duct stones.
methodsMEDLINE/PubMed and Science Citation Index databases (1990-2011) were searched for randomized, controlled trials that met the inclusion criteria for data extraction. Outcomes were calculated as odds ratios (ORs) with 95% confidence intervals (CIs) using RevMan 5.1.
resultsNine trials with 933 patients were studied. No significant differences was observed between the two groups with regard to bile duct clearance (OR, 0.89; 95% CI, 0.65-1.21), mortality (OR, 1.2; 95% CI, 0.32-4.52), total morbidity (OR, 0.75; 95% CI, 0.53-1.06), major morbidity (OR, 0.95; 95% CI, 0.60-1.52) and the need for additional procedures (OR, 1.58; 95% CI, 0.76-3.30).
conclusionsOutcomes after one-stage laparoscopic/endoscopic management of bile duct stones are no different to the outcomes after two-stage management.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.