ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2012
Factors in perioperative care that determine blood loss in liver surgery.
Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02548910 (The PRICE Trial), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The PRICE Trial: Phlebotomy Resulting in Controlled Hypovolemia to Prevent Blood Loss in Major Hepatic Resections
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Enhanced recovery following liver surgery: a systematic review and meta-analysis.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2014Pooled it
- Systematic review and meta-analysis of haemostatic and biliostatic efficacy of fibrin sealants in elective liver surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013Pooled it
- Trial
- Major liver resection, systemic fibrinolytic activity, and the impact of tranexamic acid.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2016Trial
- The impact of peri-operative blood transfusions on post-pancreatectomy short-term outcomes: an analysis from the American College of Surgeons National Surgical Quality Improvement Program.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015Trial
- Goal-Directed Fluid Therapy Using Stroke Volume Variation for Resuscitation after Low Central Venous Pressure-Assisted Liver Resection: A Randomized Clinical Trial.Journal of the American College of Surgeons · 2015Trial
- Surgeon Perspectives on Intraoperative Cell Salvage in Liver Resection for Cancer: A National Survey of Hepatopancreatobiliary Surgeons.Annals of surgical oncology · 2026Article
- Safety and outcomes of hemodilutional autologous transfusion in intermediate- to advanced-level liver resection: a prospective observational study.Surgery today · 2026Article
- Intraoperative blood loss as a predictor of outcomes in liver transplantation: determining optimal cutoff values for improved graft survival.Langenbeck's archives of surgery · 2025Observational
- Blood Type as a Potential Predictor of Hemorrhagic Risk in Patients Undergoing Partial Hepatectomy for Colorectal Liver Metastasis.Journal of clinical medicine · 2025Article
- Review
- Bilateral thoracic paravertebral block for robotic hepatectomy without hepatic portal occlusion for a cirrhosis patient: a case report.Frontiers in oncology · 2025Article
- Low versus standard central venous pressure during laparoscopic liver resection: A systematic review, meta-analysis and trial sequential analysis.Annals of hepato-biliary-pancreatic surgery · 2024Review
- Surgical outcomes of a prospective, phase 2 trial of robotic surgery for resectable right-sided colon cancer (the ROBOCOLO trial).Annals of gastroenterological surgery · 2024Article
- Article
- Optimization of a laparoscopic procedure for advanced intrahepatic cholangiocarcinoma based on the concept of "waiting time": a preliminary report.BMC cancer · 2022Article
- Article
- The survival after recurrence of colorectal cancer: a retrospective study focused on time to recurrence after curative resection.Surgery today · 2022Article
- Two-stage goal-directed therapy protocol for non-donor open hepatectomy: an interventional before-after study.Journal of anesthesia · 2019Article
- In vivo photoacoustic imaging of major blood vessels in the pancreas and liver during surgery.Journal of biomedical optics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesExcessive blood loss during liver surgery contributes to postoperative morbidity and mortality and the minimizing of blood loss improves outcomes. This study examines pre- and intraoperative factors contributing to blood loss and identifies areas for improvement.
methodsAll patients who underwent elective hepatic resection between June 2007 and June 2009 were identified. Detailed information on the pre- and perioperative clinical course was analysed. Univariate and multivariate analyses were used to identify factors associated with intraoperative blood loss.
resultsA total of 175 patients were studied, of whom 95 (54%) underwent resection of three or more segments. Median blood loss was 782 ml. Greater blood loss occurred during major resections and prolonged surgery and was associated with an increase in postoperative complications (P= 0.026). Peak central venous pressure (CVP) of >10 cm H(2)O was associated with increased blood loss (P= 0.01). Although no differences in case mix were identified, blood loss varied significantly among anaesthetists, as did intraoperative volumes of i.v. fluids and transfusion practices.
conclusionsThis study confirms a relationship between CVP and blood loss in hepatic resection. Intraoperative CVP values were higher than those described in other studies. There was variation in the intraoperative management of patients. Collaboration between surgical and anaesthesia teams is required to minimize blood loss and the standardization of intraoperative anaesthesia practice may improve outcomes following liver surgery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.