Evidence map›Paper›PMID 22403476›Full record

ArticlePersoonia2011

Waterborne Exophiala species causing disease in cold-blooded animals.

G S de Hoog, V A Vicente, M J Najafzadeh, M J Harrak, H Badali, S Seyedmousavi

Open access · greenAbstract read
In one paragraph

Article in Persoonia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 214 citations in OpenAlex.

  1. Trial
  2. Is the Exophiala complex a silent threat in Brazil? A systematic review.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  3. Article
  4. Article
  5. Two new species ofMycoKeys · 2026
    Article
  6. Article
  7. A novel case of feline Exophiala spinifera disease in Americas: review integrating diagnosis and clinical.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Review
  8. A new family of ant-associated fungi inStudies in mycology · 2025
    Article
  9. Two NovelMycobiology · 2025
    Article
  10. Article
  11. Article
  12. IMA fungus · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Unusual manifestation of pulmonaryBMJ case reports · 2023
    Article
  19. Article
  20. A Lethal Case of DisseminatedJournal of fungi (Basel, Switzerland) · 2023
    Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

G S de HoogCBS-KNAW Fungal Biodiversity Centre, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands; corresponding author e-mail: de.hoog@cbs.knaw.nl .
V A Vicente
M J Najafzadeh
M J Harrak
H Badali
S Seyedmousavi
Schlumberger (Ireland) · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of mesophilic waterborne species of the black yeast genus Exophiala (Chaetothyriales) belong to a single clade judging from SSU rDNA data. Most taxa are also found to cause cutaneous or disseminated infections in cold-blooded, water animals, occasionally reaching epidemic proportions. Hosts are mainly fish, frogs, toads, turtles or crabs, all sharing smooth, moist or mucous skins and waterborne or amphibian lifestyles; occasionally superficial infections in humans are noted. Cold-blooded animals with strictly terrestrial life styles, such as reptiles and birds are missing. It is concluded that animals with moist skins, i.e. those being waterborne and those possessing sweat glands, are more susceptible to black yeast infection. Melanin and the ability to assimilate alkylbenzenes are purported general virulence factors. Thermotolerance influences the choice of host. Exophiala species in ocean water mostly have maximum growth temperatures below 30 °C, whereas those able to grow until 33(-36) °C are found in shallow waters and occasionally on humans. Tissue responses vary with the phylogenetic position of the host, the lower animals showing poor granulome formation. Species circumscriptions have been determined by multilocus analyses involving partial ITS, TEF1, BT2 and ACT1.

Indexed as

amphibian diseaseblack yeastsChaetothyrialesExophialafish diseaselethargic crab diseasepathogenicitywaterborne fungi

Identifiers

PMID22403476
PMCPMC3251318
OpenAlexW1982117310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.