Evidence map›Paper›PMID 22403223›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2012

A literature review and survey of childhood pneumonia etiology studies: 2000-2010.

Zunera Gilani, Yuenting D Kwong, Orin S Levine, Maria Deloria-Knoll, J Anthony G Scott, Katherine L O'Brien, Daniel R Feikin

Registry-linked trialAbstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02258763 (Pneumonia in Children), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02258763 phase4completednot on this mapstarted 2014, after this paper: background citation

Pneumonia in Children: Aetiology, Ideal Antibiotic Duration, Quality of Life

TypeinterventionalSponsorUniversity of MalayaRan2014 to 2018Enrolled19ConditionsPneumoniaArmsAmoxicillin-Potassium Clavulanate Combination, Placebo
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Chest physiotherapy for pneumonia in children.The Cochrane database of systematic reviews · 2019
    Pooled it
  3. Article
  4. Article
  5. Article
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  9. Article
  10. Heightened Local TMediators of inflammation · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. The Enduring Challenge of Determining Pneumonia Etiology in Children: Considerations for Future Research Priorities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
  19. Standardization of Clinical Assessment and Sample Collection Across All PERCH Study Sites.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Zunera GilaniDepartment of Epidemiology, Bloomberg School of Public Health, Baltimore, MD 21205, USA. zgilani@jhsph.edu
Yuenting D Kwong
Orin S Levine
Maria Deloria-Knoll
J Anthony G Scott
Katherine L O'Brien
Daniel R Feikin
Johns Hopkins University · USCenters for Disease Control and Prevention · USKenya Medical Research Institute · KE

Funding

Wellcome Trust 092654
6 · The paper itself

Abstract

The Pneumonia Etiology Research for Child Health (PERCH) project is the largest multicountry etiology study of childhood pneumonia since the Board on Science and Technology in International Development studies of the 1980s. However, it is not the only recent or ongoing pneumonia etiology study, and even with seven sites, it cannot capture all epidemiologic settings in the developing world. Funding providers, researchers and policymakers rely on the best available evidence to strategically plan programs, new research directions and interventions. We aimed to describe the current landscape of recent pneumonia etiology studies in children under 5 years of age in the developed and developing world, as ascertained by a literature review of relevant studies with data since the year 2000 and a survey of researchers in the field of childhood pneumonia. We collected information on the study population, study design, case definitions, laboratory samples and methods and identified pathogens. A literature review identified 88 studies with child pneumonia etiology results. As of June 2010, our survey of researchers identified an additional 65 ongoing and recently completed child pneumonia etiology studies. This demonstrates the broad existing context into which the PERCH study must be placed. However, the landscape analysis also reveals a multiplicity of case definitions, levels of clinician involvement, facility types, specimen collection, and laboratory techniques. It reinforces the need for the standardization of methods and analyses for present and future pneumonia etiology studies in order to optimize their cumulative potential to accurately describe the microbial causes of childhood pneumonia.

Indexed as

Child WelfareChildChild, PreschoolCommunity-Acquired InfectionsData CollectionDeveloping CountriesEpidemiologic Research DesignHumansInfantPneumoniaPopulation SurveillanceTime Factors

Identifiers

PMID22403223
PMCPMC3693495
OpenAlexW2154347286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.