ArticlePediatric nephrology (Berlin, Germany)2012
Early risk factors for neonatal mortality in CAKUT: analysis of 524 affected newborns.
Article in Pediatric nephrology (Berlin, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 99 citations in OpenAlex.
- The population frequency of predicted pathogenic genetic variants in commonly affected CAKUT genes in the general population.Pediatric nephrology (Berlin, Germany) · 2026Article
- CAKUT calculator: a clinical risk prediction tool for in-hospital mortality in neonates with congenital anomalies of the kidney and urinary tract admitted to level IV NICUs.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Congenital Anomalies of Kidney and Urinary Tract in Children - Clinical Spectrum and Complications.Indian journal of pediatrics · 2026Article
- Outcome of children with fusion anomalies of the kidney: a single center experience from North India.International urology and nephrology · 2026Article
- Risk factors for perinatal and neonatal mortality in cases with congenital anomalies of the kidney and urinary tract: a nested cohort study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Assessing masked hypertension and ambulatory arterial stiffness index in children congenital kidney malformations.Clinical and experimental nephrology · 2025Article
- Epidemiology and disease burden of pediatric congenital anomalies of the kidney and urinary tract: a national cross-sectional study of hospitalized children in China.World journal of pediatrics : WJP · 2025Article
- Use of prenatal ultrasound findings to predict postnatal outcome in fetuses with lower urinary tract obstruction.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2024Article
- Nadir Creatinine in Congenital Anomalies of the Kidney and Urinary Tract (CAKUT): A Single-Center Experience.Children (Basel, Switzerland) · 2024Article
- Spectrum of congenital anomalies of the kidney and urinary tract in a pediatric nephrology clinic in Ethiopia and factors associated with advanced chronic kidney disease: A cross-sectional study.PLOS global public health · 2024Article
- Associations between maternal chronic diseases and congenital anomalies of the kidney and urinary tract in offspring: a population-based cohort study.Clinical kidney journal · 2023Article
- Kidney transplant access for children and young adults with congenital anomalies of the kidney and urinary tract.International urology and nephrology · 2023Article
- Predictive factors for survival in patients with oligohydramnios secondary to antenatal kidney disease.Pediatric nephrology (Berlin, Germany) · 2023Article
- Observed to expected lung area to head circumference ratio (O/E LHR) in fetuses with congenital anomalies of the kidney and urinary tract (CAKUT): assessment and evaluation as predictive factor for acute postnatal outcome-a single center study.Frontiers in pediatrics · 2023Article
- Analysis of the operational status of the three-level referral system for urologic ultrasound screening and risk factors for renal pelvic dilatation in high-risk children.Frontiers in pediatrics · 2023Article
- Definition, diagnosis and clinical management of non-obstructive kidney dysplasia: a consensus statement by the ERKNet Working Group on Kidney Malformations.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022Article
- Definition, diagnosis and management of fetal lower urinary tract obstruction: consensus of the ERKNet CAKUT-Obstructive Uropathy Work Group.Nature reviews. Urology · 2022Review
- Structural and functional changes in the kidney caused by adverse fetal and neonatal environments.Molecular biology reports · 2022Review
- Risk Factors Associated With Renal and Urinary Tract Anomalies Delineated by an Ultrasound Screening Program in Infants.Frontiers in pediatrics · 2021Article
- Factors Associated With the Development of Chronic Kidney Disease in Children With Congenital Anomalies of the Kidney and Urinary Tract.Frontiers in pediatrics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCongenital abnormalities of the kidney and urinary tract (CAKUT) are significant causes of morbidity. The aim of the study was to determine predictive factors of mortality in newborns with CAKUT.
methodsAll 29,653 consecutive newborns hospitalized in a tertiary neonatal unit between 1996 and 2006 were evaluated. The main outcome was neonatal mortality. The variables analyzed as risk factors were maternal age, first pregnancy, low birth weight (LBW), prematurity, oligohydramnios, and CAKUT associated with other malformations (Associated CAKUT).
resultsCAKUT was detected in 524 newborns, with an overall prevalence of 17.7 per 1,000 live births. A total of 325 (62%) cases were classified as urinary tract dilatation, 79 (15.1%) as renal cystic disease, and 120 (22.9%) as other subgroups. In the urinary tract dilatation subgroup, independent risk factors for early mortality were Associated CAKUT [odds ratio (OR) 20.7], prematurity (OR 4.5) LBW (OR 3.8), oligohydramnios (OR 3.0), and renal involvement (OR 3.0). In the renal cystic disease subgroup, two variables remained associated with neonatal mortality: LBW (OR 12.3) and Associated CAKUT (OR 21.4).
conclusionThe presence of extrarenal anomalies was a strong predictor of poor outcome in a larger series of infants with CAKUT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.