ReviewMinerva urologica e nefrologica = The Italian journal of urology and nephrology2012
Prostate cancer stem cell biology.
Review in Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative study and meta-analysis of meta-analysis studies for the correlation of genomic markers with early cancer detection.Human genomics · 2013Pooled it
- In silico identification and in vitro validation of alpha-hederin as a potent inhibitor of Wnt/β-catenin signaling pathway in breast cancer stem cells.In silico pharmacology · 2024Article
- Melanoma stem cell vaccine induces effective tumor immunity against melanoma.Human vaccines & immunotherapeutics · 2023Article
- Tumor Chemosensitivity Assays Are Helpful for Personalized Cytotoxic Treatments in Cancer Patients.Medicina (Kaunas, Lithuania) · 2021Review
- Targeting Radiation-Resistant Prostate Cancer Stem Cells by B7-H3 CAR T Cells.Molecular cancer therapeutics · 2021Article
- Protein Expression Analysis of an In Vitro Murine Model of Prostate Cancer Progression: Towards Identification of High-Potential Therapeutic Targets.Journal of personalized medicine · 2020Article
- Article
- Effect of CD133 overexpression on bone metastasis in prostate cancer cell line LNCaP.Oncology letters · 2019Article
- Regulation of Osteosclerosis by Inoculated Cd133JBMR plus · 2019Article
- Evaluation of the effect of hyperthermia and electron radiation on prostate cancer stem cells.Radiation and environmental biophysics · 2018Article
- Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer.Oncotarget · 2017Article
- Article
- Article
- Expression of cancer stem cell biomarkers as a tool for a correct therapeutic approach to hepatocellular carcinoma.Oncoscience · 2015Review
- Targeting CSCs in tumor microenvironment: the potential role of ROS-associated miRNAs in tumor aggressiveness.Current stem cell research & therapy · 2014Review
- Cancer stem cells in prostate cancer.Translational andrology and urology · 2013Review
- Overview of cancer stem cells (CSCs) and mechanisms of their regulation: implications for cancer therapy.Current protocols in pharmacology · 2013Review
- Targeting CSC-related miRNAs for cancer therapy by natural agents.Current drug targets · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The cancer stem cell (CSC) model provides insights into pathophysiology of cancers and their therapeutic response. The CSC model has been both controversial, yet provides a foundation to explore cancer biology. In this review, we provide an overview of CSC concepts, biology and potential therapeutic avenues. We then focus on prostate CSC including 1) their purported origin as either basal-derived or luminal-derived cells; 2) markers used for prostate CSC identification; 3) alterations of signaling pathways in prostate CSCs; 4) involvement of prostate CSCs in metastasis of PCa; and 5) microRNA-mediated regulation of prostate CSCs. Although definitive evidence for the identification and characterization of prostate CSCs still remains unclear, future directions pursuing therapeutic targets of CSCs may provide novel insights for the treatment of PCa.
Indexed as
Identifiers
22402315PMC3332041What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.