Evidence map›Paper›PMID 22401500›Full record

ArticleNanoscale research letters2012

Rapid identification of Mycobacterium tuberculosis infection by a new array format-based surface plasmon resonance method.

Shang-Chen Hsieh, Chia-Chen Chang, Chia-Chen Lu, Chia-Fong Wei, Chuan-Sheng Lin, Hsin-Chih Lai, Chii-Wann Lin

Open access · goldAbstract read
In one paragraph

Article in Nanoscale research letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Article
  3. Cure of tuberculosis using nanotechnology: An overview.Journal of microbiology (Seoul, Korea) · 2018
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Development of sandwich-form biosensor to detect Mycobacterium tuberculosis complex in clinical sputum specimens.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shang-Chen HsiehGraduate Institute of Medical Biotechnology and Laboratory Science, and Research Center for Pathogenic Bacteria, Chang Gung University, No, 259, Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, 333, Taiwan. hclai@mail.cgu.edu.tw.
Chia-Chen Chang
Chia-Chen Lu
Chia-Fong Wei
Chuan-Sheng Lin
Hsin-Chih Lai
Chii-Wann Lin
Chang Gung University · TWNational Taiwan University · TWFu Jen Catholic University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tubercle bacillus [TB] is one of the most important chronic infectious diseases that cause millions of deaths annually. While conventional smear microscopy and culture methods are widely used for diagnosis of TB, the former is insensitive, and the latter takes up to 6 to 8 weeks to provide a result, limiting the value of these methods in aiding diagnosis and intermediate decisions on treatment. Therefore, a rapid detection method is essential for the diagnosis, prognosis assessment, and recurrence monitoring. A new surface plasmon resonance [SPR] biosensor based on an array format, which allowed immobilizing nine TB antigens onto the sensor chip, was constructed. Simultaneous determination of multiple TB antibodies in serum had been accomplished with this array-based SPR system. The results were compared with enzyme-linked immunosorbent assay, a conventional immunological method. Array-based SPR showed more advantages in providing label-free and real-time detection. Additionally, the high sensitivity and specificity for the detection of TB infection showed its potential for future development of biosensor arrays for TB diagnosis.

Identifiers

PMID22401500
PMCPMC3317816
OpenAlexW2169950417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.