ArticlePhysical review letters2012
Biological ferroelectricity uncovered in aortic walls by piezoresponse force microscopy.
Article in Physical review letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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Who cites it
29 citing papers in PubMed, 165 citations in OpenAlex.
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- Reply to: On the giant deformation and ferroelectricity of guanidinium nitrate.Nature communications · 2025Article
- Self-Assembled Piezoelectric Films from Aligned Lysozyme Protein Fibrils.Biomacromolecules · 2025Article
- Discovery of molecular ferroelectric catalytic annulation for quinolines.Nature communications · 2024Article
- Molecular self-assembled helix peptide nanotubes based on some amino acid molecules and their dipeptides: molecular modeling studies.Journal of molecular modeling · 2024Article
- Flexible, biodegradable ultrasonic wireless electrotherapy device based on highly self-aligned piezoelectric biofilms.Science advances · 2024Article
- Piezoelectricity of BiNanomaterials (Basel, Switzerland) · 2023Article
- Active self-assembly of piezoelectric biomolecular films via synergistic nanoconfinement and in-situ poling.Nature communications · 2023Article
- Piezoelectric and Magnetically Responsive Biodegradable Composites with Tailored Porous Morphology for Biotechnological Applications.ACS applied polymer materials · 2022Article
- Manipulation of coacervate droplets with an electric field.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- A small-molecule organic ferroelectric with piezoelectric voltage coefficient larger than that of lead zirconate titanate and polyvinylidene difluoride.Chemical science · 2022Article
- Ferroelectric-like Behavior Originating from Oxygen Vacancy Dipoles in Amorphous Film for Non-volatile Memory.Nanoscale research letters · 2020Article
- The Vegetative Receptor-Vascular Reflex (VRVR) - A New Key to Regeneration.Frontiers in physiology · 2020Article
- Self-assembly of dipeptide Boc-diphenylalanine nanotubes inside electrospun polymeric fibers with strong piezoelectric response.Nanoscale advances · 2019Article
- Room temperature ferroelectricity in fluoroperovskite thin films.Scientific reports · 2017Article
- Cellulose-based magnetoelectric composites.Nature communications · 2017Article
- Fabrication and in vitro biological properties of piezoelectric bioceramics for bone regeneration.Scientific reports · 2017Article
- The Coupled Bio-Chemo-Electro-Mechanical Behavior of Glucose Exposed Arterial Elastin.Journal of physics D: Applied physics · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Many biological tissues are piezoelectric and pyroelectric with spontaneous polarization. Ferroelectricity, however, has not been reported in soft biological tissues yet. Using piezoresponse force microscopy, we discover that the porcine aortic walls are not only piezoelectric, but also ferroelectric, with the piezoelectric coefficient in the order of 1 pm/V and coercive voltage approximately 10 V. Through detailed switching spectroscopy mapping and relaxation studies, we also find that the polarization of the aortic walls is internally biased outward, and the inward polarization switched by a negative voltage is unstable, reversing spontaneously to the more stable outward orientation shortly after the switching voltage is removed. The discovery of ferroelectricity in soft biological tissues adds an important dimension to their biophysical properties, and could have physiological implications as well.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.