Trial reportTelemedicine journal and e-health : the official journal of the American Telemedicine Association2012
Efficacy of telemedicine for stroke: pooled analysis of the Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC) and STRokE DOC Arizona telestroke trials.
Trial report in Telemedicine journal and e-health : the official journal of the American Telemedicine Association, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 5 syntheses or guidelines pooled it, 149 citations in OpenAlex.
- Telehealth-guided provider-to-provider communication to improve rural health: A systematic review.Journal of telemedicine and telecare · 2024Pooled it
- A topical review of the feasibility and reliability of ambulance-based telestroke.Frontiers in stroke · 2024Pooled it
- Telemedicine in Neurosurgery: Lessons Learned from a Systematic Review of the Literature for the COVID-19 Era and Beyond.Neurosurgery · 2020Pooled it
- Interactive telemedicine: effects on professional practice and health care outcomes.The Cochrane database of systematic reviews · 2015Pooled it
- Systematic review of telestroke for post-stroke care and rehabilitation.Current atherosclerosis reports · 2013Pooled it
- Trial
- Holo-Stroke-ii: Stroke care through stroke hologram teleportation- inpatient immersion.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2026Article
- Telestroke management during the Hajj seasons 2023-2024: insights from SEHA Virtual Hospital in KSA.Frontiers in neurology · 2025Article
- Availability & Applicability of the National Institute of Health Stroke Scale at Time of Imaging Interpretation for Code Stroke in the Community Hospital Setting.Journal of the Belgian Society of Radiology · 2025Article
- In-hospital stroke protocol outcomes before and after the implementation of neurological assessments by telemedicine: an observational case-control study.Frontiers in neurology · 2024Article
- Teleneurocritical Care for Patients with Large Vessel Occlusive Ischemic Stroke Treated by Thrombectomy.Neurocritical care · 2023Article
- Nursing Home-Sensitive Hospitalizations and the Relevance of Telemedicine: A Scoping Review.International journal of environmental research and public health · 2022Article
- Article
- Telemedicine during and post-COVID 19: The insights of neurosurgery patients and physicians.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2022Article
- Stroke Telemedicine for Arizona Rural Residents, the Legacy Telestroke Study.Telemedicine reports · 2022Article
- Telehealth in emergency medicine: A consensus conference to map the intersection of telehealth and emergency medicine.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2021Article
- Health technology assessment of telemedicine applications in Northern borders of India.Medical journal, Armed Forces India · 2021Article
- Telestroke Across the Continuum of Care: Lessons from the COVID-19 Pandemic.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021Article
- Intravenous Thrombolysis by Telestroke in the 3- to 4.5-h Time Window.Frontiers in neurology · 2021Article
- Distance Neurological Supervision Using Telestroke Does Not Increase Door-to-Needle Time in Acute Ischemic Stroke Management: The Experience of Two Regional Stroke Units.Frontiers in neurology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeTelemedicine can disseminate vascular neurology expertise and optimize recombinant tissue plasminogen activator (rt-PA) use for acute ischemic stroke in rural underserved communities. The purpose of this study was to prospectively assess whether telemedicine or telephone was superior for decision-making.
methodsThe study design is a pooled analysis of two identically designed randomized controlled trials conducted in a multistate hub and spoke telestroke network setting with acute stroke syndrome patients, comparing telemedicine versus telephone-only consultations. From each trial, common data elements were pooled to assess, principally, for correctness of thrombolysis decision-making. Secondary outcomes included rt-PA use rate, 90-day functional outcome, post-thrombolysis intracranial hemorrhage, and data completeness.
resultsTwo hundred seventy-six pooled patients were evaluated. Correct thrombolysis eligibility decisions were made more often with telemedicine (96% telemedicine, 83% telephone; odds ratio [OR] 4.2; 95% confidence interval [CI] 1.69-10.46; p=0.002). Intravenous rt-PA usage was 26% (29% telemedicine, 24% telephone; OR 1.27; 95% CI 0.71-2.25; p=0.41). Ninety-day outcomes were not different for Barthel Index, modified Rankin Scale, or mortality. There was no difference in post-thrombolysis intracranial hemorrhage (8% telemedicine, 6% telephone; p>0.999).
conclusionsThis pooled analysis supports the hypothesis that stroke telemedicine consultations, compared with telephone-only, result in more accurate decision-making. Together with high rt-PA utilization rate, low post-rt-PA intracranial hemorrhage rate, and acceptable patient outcome, the results confirm that telemedicine is a viable consultative tool for acute stroke. The replication of the hub and spoke network infrastructure supports the generalizability of telemedicine when used in broader settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.