ReviewAdvances in experimental medicine and biology2012
Physiology and pathophysiology of mitochondrial DNA.
Review in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Mitochondrial transplantation in lung diseases: From mechanisms to application prospects.Genes & diseases · 2026Review
- Possible Role of Mitochondrial Transfer RNA Gene 5816 A > G Genetic Polymorphism (m.5816A > G) in a 3-Year-Old Child with Dystonia: Report of a Case.Global medical genetics · 2023Article
- Mitochondrial DNA Polymorphism in HV1 and HV2 Regions and 12S rDNA in Perimenopausal Hypertensive Women.Biomedicines · 2023Article
- Decrease of MtDNA copy number affects mitochondrial function and involves in the pathological consequences of ischaemic stroke.Journal of cellular and molecular medicine · 2022Article
- The Role of Mitochondrial Genes in Neurodegenerative Disorders.Current neuropharmacology · 2022Review
- The heterogeneity among subgroups of haplogroup J influencing Alzheimer's disease risk.Journal of advanced research · 2021Article
- Detection of somatic mutations in the mitochondrial DNA control region D-loop in brain tumors: The first report in Malaysian patients.Oncology letters · 2017Article
- The Landscape of mtDNA Modifications in Cancer: A Tale of Two Cities.Frontiers in oncology · 2017Review
- Mitochondrial Epigenetics and Environmental Exposure.Current environmental health reports · 2016Review
- Mitochondrial DNA 4977-base pair common deletion in blood leukocytes and melanoma risk.Pigment cell & melanoma research · 2016Article
- Article
- Mutational patterns in the breast cancer mitochondrial genome, with clinical correlates.Carcinogenesis · 2014Article
- Import of desired nucleic acid sequences using addressing motif of mitochondrial ribosomal 5S-rRNA for fluorescent in vivo hybridization of mitochondrial DNA and RNA.Journal of bioenergetics and biomembranes · 2014Article
- Somatic mitochondrial DNA mutations in Chinese patients with osteosarcoma.International journal of experimental pathology · 2013Article
- Prevalent coordination of mitochondrial DNA transcription and initiation of replication with the cell cycle.Nucleic acids research · 2013Article
- Metabolic dysfunction and mitochondrial failure in Alzheimer's disease: integrating pathophysiology, clinical evidence and emerging interventions.Frontiers in neurologyReview
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Mitochondria are the only organelles in animal cells which possess their own genomes. Mitochondrial DNA (mtDNA) alterations have been associated with various human conditions. Yet, their role in pathogenesis remains largely unclear. This review focuses on several major features of mtDNA: (1) mtDNA haplogroup, (2) mtDNA common deletion, (3) mtDNA mutations in the control region or D-loop, (4) mtDNA copy number alterations, (5) mtDNA mutations in translational machinery, (6) mtDNA mutations in protein coding genes (7) mtDNA heteroplasmy. We will also discuss their implications in various human diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.