Evidence map›Paper›PMID 22399411›Full record

ArticleJournal of autism and developmental disorders2012

Parental occupational exposures and autism spectrum disorder.

Erin C McCanlies, Desta Fekedulegn, Anna Mnatsakanova, Cecil M Burchfiel, Wayne T Sanderson, Luenda E Charles, Irva Hertz-Picciotto

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  7. Review
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  11. Article
  12. Severity of ASD symptoms and their correlation with the presence of copy number variations and exposure to first trimester ultrasound.Autism research : official journal of the International Society for Autism Research · 2017
    Article
  13. Environmental factors associated with autism spectrum disorder: a scoping review for the years 2003-2013.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2017
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. A twin study of heritable and shared environmental contributions to autism.Journal of autism and developmental disorders · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Erin C McCanliesNational Institute for Occupational Safety and Health, 1095 Willowdale Rd., Morgantown, WV 26505, USA.
Desta Fekedulegn
Anna Mnatsakanova
Cecil M Burchfiel
Wayne T Sanderson
Luenda E Charles
Irva Hertz-Picciotto
National Institute for Occupational Safety and Health · USUniversity of California, Davis · USUniversity of Kentucky · US

Funding

THE CHARGE STUDY: CHILDHOOD AUTISM RISKS FROM GENETICS AND THE ENVIRONMENT - ADMINISTRATIVE SUPPLEMENTR01ES015359 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HERTZ-PICCIOTTO, IRVA · 2007 to 2019
$13.8M
UC Davis Center for Children's Environmental Health (CCEH)P01ES011269 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI VAN DE WATER, JUDY A. · 2001 to 2018
$12.5M
NIEHS NIH HHS 1 P01 ES11269NIEHS NIH HHS 1 R01 ES015359
6 · The paper itself

Abstract

Both self-report and industrial hygienist (IH) assessed parental occupational information were used in this pilot study in which 174 families (93 children with ASD and 81 unaffected children) enrolled in the Childhood Autism Risks from Genetics and Environment study participated. IH results indicated exposures to lacquer, varnish, and xylene occurred more often in the parents of children with ASD compared to the parents of unaffected children. Parents of children with ASD were more likely to report exposures to asphalt and solvents compared to parents of unaffected children. This study was limited by the small sample size, but results suggest that workplace exposures to some chemicals may be important in the etiology of ASD and deserve further investigation.

Indexed as

ParentsChild Development Disorders, PervasiveChild, PreschoolFemaleHumansMaleOccupational ExposurePilot Projects

Identifiers

PMID22399411
OpenAlexW2032464967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.