ArticleAdvances in experimental medicine and biology2012
MHC signaling during social communication.
Article in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 64 citations in OpenAlex.
- Parental kinship coefficient but not paternal coloration predicts early offspring growth in lake char.Heredity · 2024Article
- Response to MHC-based olfactory cues in a mate choice context in two species of darter (Percidae: Etheostoma).Ecology and evolution · 2024Article
- Neurobiology of Pathogen Avoidance and Mate Choice: Current and Future Directions.Animals : an open access journal from MDPI · 2024Review
- Feather chemicals contain information about the major histocompatibility complex in a highly scented seabird.Proceedings. Biological sciences · 2022Article
- Functional Protein Composition in Femoral Glands of Sand Lizards (Molecules (Basel, Switzerland) · 2022Article
- No evidence for a relationship between MHC heterozygosity and life history strategy in a sample of North American undergraduates.Scientific reports · 2020Article
- Pleasant body odours, but not genetic similarity, influence trustworthiness in a modified trust game.Scientific reports · 2020Article
- Embryo survival in the oviduct not significantly influenced by major histocompatibility complex social signaling in the horse.Scientific reports · 2020Article
- Reverse Signaling by MHC-I Molecules in Immune and Non-Immune Cell Types.Frontiers in immunology · 2020Review
- Genetic variation at MHC class II loci influences both olfactory signals and scent discrimination in ring-tailed lemurs.BMC evolutionary biology · 2019Article
- MHC class I diversity predicts non-random mating in Chinese alligators (Alligator sinensis).Heredity · 2019Article
- Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders.World journal of stem cells · 2019Review
- A predicted interaction between odour pleasantness and intensity provides evidence for major histocompatibility complex social signalling in women.Proceedings. Biological sciences · 2018Article
- Cycle-specific female preferences for visual and non-visual cues in the horse (Equus caballus).PloS one · 2018Article
- Major histocompatibility complex-linked social signalling affects female fertility.Proceedings. Biological sciences · 2017Article
- A polychromatic 'greenbeard' locus determines patterns of cooperation in a social amoeba.Nature communications · 2017Article
- Odour-based discrimination of similarity at the major histocompatibility complex in birds.Proceedings. Biological sciences · 2017Article
- The Presence Of Strange Males' Odor Induces Behavioral Responses And Elevated Levels Of Low Molecular Weight Proteins Excreted In The Urine Of Mature Water Vole Males (Arvicola amphibius L).Journal of chemical ecology · 2016Article
- Female major histocompatibility complex type affects male testosterone levels and sperm number in the horse (Equus caballus).Proceedings. Biological sciences · 2015Article
- Preen secretions encode information on MHC similarity in certain sex-dyads in a monogamous seabird.Scientific reports · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The major histocompatibility complex (MHC) has been known to play a critical role in immune recognition since the 1950s. It was a surprise, then, in the 1970s when the first report appeared indicating MHC might also function in social signaling. Since this seminal discovery, MHC signaling has been found throughout vertebrates and its known functions have expanded beyond mate choice to include a suite of behaviors from kin-biased cooperation, parent-progeny recognition to pregnancy block. The widespread occurrence of MHC in social signaling has revealed conserved behavioral-genetic mechanisms that span vertebrates and includes humans. The identity of the signal's chemical constituents and the receptors responsible for the perception of the signal have remained elusive, but recent advances have enabled the identification of the key components of the behavioral circuit. In this chapter we organize recent findings from the literature and discuss them in relation to four nonmutually exclusive models wherein MHC functions as a signal of (i) individuality, (ii) relatedness, (iii) genetic compatibility and (iv) quality. We also synthesize current mechanistic studies, showing how knowledge about the molecular basis of MHC signaling can lead to elegant and informative experimental manipulations. Finally, we discuss current evidence relating to the primordial functions of the MHC, including the possibility that its role in social signaling may be ancestral to its central role in adaptive immunity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.