ArticleBrain and behavior2011
Challenges in diagnosis of isolated central nervous system vasculitis.
Article in Brain and behavior, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Primary Angiitis of the CNS: A Systematic Review and Meta-analysis.Neurology(R) neuroimmunology & neuroinflammation · 2021Pooled it
- Intersection of Autoimmunity: NMDA Positivity, Hypertrophic Pachymeningitis, and Primary CNS Angiitis in a Single Patient - A Diagnostic Challenge.Annals of Indian Academy of Neurology · 2025Article
- Predictive Value of Clinical, CSF and Vessel Wall MRI Variables in Diagnosing Primary Angiitis of the CNS.Neurology. Clinical practice · 2024Article
- Challenging presentation of primary vasculitis of the central nervous system.Cerebral circulation - cognition and behavior · 2021Article
- Primary Angiitis of the Center Nervous System: A Clinical Challenge Diagnosed Postmortem.Case reports in neurological medicine · 2017Article
- Rapidly progressive dementia and ataxia in an elderly man.Practical neurology · 2013Article
- Headache and vasculitis.Current pain and headache reports · 2013Review
- Primary angiitis of the central nervous system: a report of three cases from a single colombian center.Case reports in neurological medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Isolated central nervous system (CNS) vasculitis is a rare and complicated disorder. Patients typically present with nonspecific neurologic symptoms such as headache and encephalopathy, and have variable progression and severity of the disease. Challenges to definitive diagnosis include the limitations of currently available diagnostic modalities with high likelihood of false-positive or false-negative findings. Imaging, serologic, and cerebrospinal fluid (CSF) evaluation, and even angiography can fail to establish the diagnosis. Often, brain biopsy is required. In order to illustrate these challenges, we report the case of a patient who presented with subacute cognitive decline and was ultimately diagnosed with isolated CNS eosinophilic vasculitis. Initial work-up included CSF and serologic analyses, magnetic resonance imaging (MRI), and cerebral angiography, but definitive diagnosis required brain biopsy. Immunosuppressive therapy resulted in clinical improvement and stabilization. To our knowledge, only one other case of isolated CNS eosinophilic vasculitis has been reported in the literature. We discuss the importance of a high index of clinical suspicion in cases of progressive nonspecific neurologic symptoms.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.