Trial reportPsychotherapy and psychosomatics2012
Outcomes of acute phase cognitive therapy in outpatients with anxious versus nonanxious depression.
Trial report in Psychotherapy and psychosomatics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00118404 (Prophylactic Cognitive Therapy for Depression.), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prophylactic Cognitive Therapy for Depression.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evaluating the effects of tDCS on depressive and anxiety symptoms from a transdiagnostic perspective: a systematic review and meta-analysis of randomized controlled trials.Translational psychiatry · 2024Pooled it
- Neuromodulation Treatments of Pathological Anxiety in Anxiety Disorders, Stressor-Related Disorders, and Major Depressive Disorder: A Dimensional Systematic Review and Meta-Analysis.Frontiers in psychiatry · 2022Pooled it
- Anxious depression as a clinically relevant subtype of pediatric major depressive disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2019Trial
- D-cycloserine augmentation of cognitive behavioral group therapy of social anxiety disorder: prognostic and prescriptive variables.Journal of consulting and clinical psychology · 2013Trial
- Preventing depressive relapse and recurrence in higher-risk cognitive therapy responders: a randomized trial of continuation phase cognitive therapy, fluoxetine, or matched pill placebo.JAMA psychiatry · 2013Trial
- Novel Psychological Interventions in the Treatment of Unipolar Major Depression.Advances in experimental medicine and biology · 2026Review
- Association between depression and endometriosis using data from NHANES 2005-2006.Scientific reports · 2023Article
- Prevalence and correlates of severe anxiety in patients with first hospitalization for major depressive disorder combined with dyslipidemia: a large sample cross-sectional study.Frontiers in psychiatry · 2023Article
- A machine learning ensemble to predict treatment outcomes following an Internet intervention for depression.Psychological medicine · 2019Article
- The Role of Dyadic Discord in Outcomes in Acute Phase Cognitive Therapy for Adults With Recurrent Major Depressive Disorder.Behavior therapy · 2019Article
- Do comorbid social and other anxiety disorders predict outcomes during and after cognitive therapy for depression?Journal of affective disorders · 2019Article
- Using patient self-reports to study heterogeneity of treatment effects in major depressive disorder.Epidemiology and psychiatric sciences · 2017Review
- Identifying moderators of the adherence-outcome relation in cognitive therapy for depression.Journal of consulting and clinical psychology · 2015Article
- Predictors of Response to Web-Based Cognitive Behavioral Therapy With High-Intensity Face-to-Face Therapist Guidance for Depression: A Bayesian Analysis.Journal of medical Internet research · 2015Article
- Baseline working memory activation deficits in dimensional anxious depression as detected by magnetoencephalography.Acta neuropsychiatrica · 2015Article
- Treating co-occurring depression and anxiety: modeling the dynamics of psychopathology and psychotherapy using the time-varying effect model.Journal of consulting and clinical psychology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveCompared to nonanxious depressed patients, anxious depressed patients respond less to pharmacotherapy, prompting consideration of alternate treatments. Based on the transdiagnostic principles of cognitive therapy (CT), we predicted that anxious depressed patients would respond as well to CT as nonanxious depressed patients.
methodAdults (n = 523) with recurrent major depressive disorder received 12-14 weeks of CT as part of the Continuation Phase Cognitive Therapy Relapse Prevention Trial. Anxious depressed patients (n = 264; 50.4%) were compared to nonanxious depressed patients (n = 259; 49.6%) on demographic variables, initial severity, attrition, and rates and patterns of response and remission.
resultsAnxious depressed patients presented with greater illness severity and had significantly lower response (55.3 vs. 68.3%) and remission rates (26.9 vs. 40.2%) based on clinician-administered measures. By contrast, smaller between-group differences for attrition, and for response (59.1 vs. 64.9%) and remission (41.7 vs. 48.7%) rates on self-report measures were not significant. Further, anxious depressed patients had greater speed of improvement on self-reported anxiety symptom severity and clinician-rated depressive and anxiety symptom severity measures.
conclusionConsistent with prior reports, anxious depressed patients presented with greater severity and, following CT, had lower response and remission rates on clinician-administered scales. However, anxious depressed patients improved more rapidly and response and remission rates on self-report measures were not significantly different from nonanxious depressed patients. Our findings suggest that anxious depressed patients may simply need additional time or more CT sessions to reach outcomes fully comparable to those of less anxious patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.